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medicalmeds.eu Medicines Antiallergic means - H1 - histamine receptors a blocker. Хлоропирамин-Ферейн®

Хлоропирамин-Ферейн®

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Producer: CJSC Bryntsalov-A Russia

Code of automatic telephone exchange: D04AA09, R06AC03

Release form: Firm dosage forms. Tablets.

Indications to use: Allergic conjunctivitis. Vasculomotor rhinitis. Small tortoiseshell. Hay fever. Quincke's disease of Quincke. Serum disease. Medicinal rash. Atopic dermatitis. Contact dermatitis. Toksikodermiya. Eczema.


General characteristics. Structure:

Active ingredient: 25 mg of Chloropyraminum of a hydrochloride in 1 tablet.

Auxiliary substances - lactose, starch corn, amylopectin, talc, gelatin, magnesium stearate.




Pharmacological properties:

Pharmacodynamics. The blocker of H1-histamine receptors, renders sedative, somnolent, antihistaminic and M-holinoblokiruyushchee action, has antiemetic effect, moderate spasmolytic and peripheral holinoblokiruyushchy activity.

Pharmacokinetics. At oral administration it is almost completely absorbed from digestive tract. The maximum concentration in blood is reached during 2 h, the therapeutic level of concentration remains 4-6 h.

It is well distributed in an organism, including the central nervous system. It is intensively metabolized in a liver. It is removed by kidneys and through intestines.


Indications to use:

Allergic conjunctivitis, vasculomotor rhinitis, small tortoiseshell, hay fever, Quincke's edema, serum disease, medicinal rash, skin diseases (atopic dermatitis, contact dermatitis, toksikodermiya, eczema).


Route of administration and doses:

Inside, during food, the adult - on 25-50 mg (1-2 tablets) 3-4 times a day.

To children aged from 1 up to 12 months - on 6,25 mg, 1-6 years - on 8,3 mg, from 7 to 14 years - on 12,5 mg, frequency rate of reception - 2-3 times a day.


Features of use:

During treatment it is necessary to abstain from potentially dangerous types of activity requiring special attention.

The ethanol use is inadmissible.


Side effects:

Dizziness, weakness, drowsiness, dryness in a mouth, nausea, diarrhea, a gastralgia, a lack of coordination of movements.


Interaction with other medicines:

Strengthens action of means for the general anesthesia, hypnotic drugs, sedative drugs, opioid analgetics, local anesthetics.

It is not compatible to ethanol.

Tricyclic antidepressants strengthen M-holinoblokiruyushchee and the oppressing action on the central nervous system.

Caffeine and Phenaminum reduce the oppressing action by the central nervous system.


Contraindications:

Hypersensitivity, pregnancy, the lactation period, closed-angle glaucoma, prostate hyperplasia, respiratory insufficiency, concomitant use of monoamine oxidase inhibitors, early chest age (up to 1 month).

With care: a round ulcer of digestive tract, reception of monoamine oxidase inhibitors, etc. the drugs oppressing the central nervous system.


Overdose:

Symptoms: children have an excitement, uneasiness, hallucinations, an athetosis, an ataxy, spasms, a mydriasis, an immovability of pupils, a dermahemia of the person, a hyperthermia; then - a vascular collapse, a coma. Adults have a block, a depression, a hyperthermia and a hyperemia of integuments, psychomotor excitement, spasms, a coma.

Treatment: a gastric lavage, reception of absorbent carbon (when carrying out a detoxication in early terms after oral administration); symptomatic therapy (including purpose of antiepileptic means, caffeine, Phenaminum), resuscitation actions, artificial ventilation of the lungs - according to indications.


Storage conditions:

In the dry, protected from light place, at a temperature not above 25 °C. Drug should be stored in the places unavailable to children. A period of validity - 5 years. Not to use drug after the expiry date specified on packaging.


Issue conditions:

According to the recipe


Packaging:

Tablets on 25 mg. Packaging: on 20, 50 tablets in banks of orange glass, in banks from glass melt. On 20, 50 tablets in banks polymeric with the screwed cover. On 10 tablets in a blister strip packaging. One bank or 1, 2, 3, 4, 5 blister strip packagings in a pack.



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