Diazolinum

General characteristics. Structure:

Active agent: Diazolinum (a mebgidrolina нападизилат) – 50 mg or 100 mg.

Pharmacological properties:

Diazolinum - a blocker histamine H1 receptors. Renders antiallergic, antipruritic, antivoeksudativny, and also weak sedative action. Blocks histamine H1 receptors, lowers a tone of smooth muscles (bronchial tubes, a GIT, a uterus), reduces permeability of capillaries and edematization, prevents developing of an itch.

Indications to use:

Allergic rhinitis (seasonal, chronic), pollinosis, allergic conjunctivitis, small tortoiseshell, Quincke's edema, pruritic dermatosis (eczema, neurodermatitis, etc.), skin reaction to stings of insects; allergic reactions to drug intake, food, etc.; combination therapy of a pruritic dermatosis and bronchial asthma.

Route of administration and doses:

Diazolinum is appointed inside after food.
To adults and children 10 years are more senior: on 50-300 mg a day. The maximum single dose - 300 mg, daily - 600 mg.
Children are 5-10 years old: 100-200 mg a day.
Children are 2-5 years old: 50-150 mg a day.

Features of use:

With care appoint at pregnancy and feeding a breast.
Care is necessary also when using against the background of diseases of a liver and kidneys (dose adjustment and intervals between receptions is possible).
With care appoint drug to the patients who are engaged in potentially dangerous types of activity requiring special attention and bystry psychomotor reactions

Side effects:

- From a nervous system and sense bodys: increased fatigue, delay of speed of reactions, dizziness, drowsiness, paresthesias.
- From bodies of a GIT: dryness in a mouth, heartburn, nausea, pain in epigastriums.
- Other: disturbance of an urination, allergic reactions, granulocytopenia, agranulocytosis.

Interaction with other medicines:

Diazolinum strengthens action of means, the oppressing TsNS.

Contraindications:

Prostatauxe, closed-angle glaucoma, peptic ulcer of a stomach and duodenum, inflammatory gastrointestinal diseases in an aggravation phase; hypersensitivity to a mebgidrolin, children's age up to 2 years.
Restrictions to use:
Pylorostenosis, epilepsy, disturbance of a cordial rhythm.

Overdose:

There are no data.

Storage conditions:

In the dry, protected from light place, at a temperature below 25 °C.

Issue conditions:

According to the recipe

Packaging:

Tablets on 50 mg and 100 mg.