Diazolin-Darnitsa
Producer: CJSC Pharmaceutical Firm Darnitsa Ukraine
Code of automatic telephone exchange: R06AX15
Release form: Firm dosage forms. Tablets.
General characteristics. Structure:
Active ingredient: mebhydrolin;
1 tablet contains a mebgidrolin of 100 mg;
excipients: lactoses monohydrate, cellulose microcrystallic, potato starch, povidone, silicon dioxide colloid anhydrous, magnesium stearate.
Pharmacological properties:
Mebgidrolin treats antihistaminic drugs, is a blocker of Hl-histamine receptors. Mebgidrolin weakens spazmogenny effect of a histamine concerning unstriated muscles of bronchial tubes, intestines, and also its influence on permeability of vessels.
Mebgidrolin is quickly soaked up from a digestive tract. Bioavailability fluctuates within 40-60%. The therapeutic effect is reached in 15-30 min., the maximum action is noted in 1-2 h. Drug practically does not get through a blood-brain barrier, is metabolized in a liver by methylation, removed from an organism by kidneys.
Indications to use:
Prevention and treatment of allergic rhinitis (allergic, chronic), a pollinosis, a small tortoiseshell, a food and medicamentous allergy, a dermatosis which are followed by a skin itch (eczema, neurodermatitis).
Route of administration and doses:
Diazolin-Darnitsa appoint inside after food to adults and children 12 years on 100-200 mg 1-2 times a day are more senior. The maximum single dose – 300 mg, daily – 600 mg. To children 6 years are more senior appoint 50 mg (½ tablets) 1-3 times a day. The course of treatment depends on the nature of a disease and the reached therapeutic effect.
Features of use:
Appropriate actions of safety at use.
During treatment it is not recommended to take alcoholic beverages and drugs which contain ethanol.
With care to appoint drug sick at zakrytouglovy glaucoma, a pylorostenosis, epilepsy, disturbances of a cordial rhythm.
With care to apply at a liver and/or renal failure (dose adjustment and intervals between receptions can be required).
Side effects:
From a nervous system and sense bodys: insanity, paresthesias, increased fatigue, drowsiness, illegibility of visual perception, delay of speed of reactions.
From bodies of digestive tract: dryness in a mouth, the dispeptic phenomena (heartburn, nausea, pain in epigastric area).
From urinogenital system: disturbance of an urination.
From system of a krovoobrazovaniye: granulocytopenia and agranulocytosis.
Others: allergic reactions.
Interaction with other medicines:
Diazolin-Darnitsa exponentiates effect of somnolent, sedative and other drugs which oppress the central nervous system.
Contraindications:
Individual hypersensitivity to drug components, a round ulcer of a stomach and duodenum, inflammatory diseases of a digestive tract, a prostatauxe.
Use during pregnancy or feeding by a breast.
Drug Diazolin-Darnitsa is contraindicated during pregnancy or feeding by a breast.
Ability to influence speed of response at control of motor transport or work with other mechanisms.
During treatment it is necessary to be kept from control of motor transport and occupations by potentially dangerous types of activity which demand concentration of attention and speed of psychomotor reactions.
Children.
Drug is not appointed to children up to 6 years.
Overdose:
Symptoms: confusion of consciousness, drowsiness, a lack of coordination of movements, dryness in a mouth.
Treatment: appoint a gastric lavage to pure washing water, absorbent carbon inside, an artificial diuresis. Further treatment – symptomatic.
Storage conditions:
Issue conditions:
Without recipe
Packaging:
On 10 tablets in a blister strip packaging, on 1 blister strip packaging in a pack.