Lorageksal

General characteristics. Structure:

Active agent – лоратадин (10 mg).

Excipients - lactose, magnesium stearate, corn starch, silicon dioxide.

Pharmacological properties:

Lorageksal (лоратадин) – the H1-antihistaminic drug which is not possessing the central and antikholdinergichesky action. At intake drug is well soaked up from zheludochno – an intestinal path. Absorption of drug does not depend on meal.
Effect of drug begins in 30 minutes after reception of one tablet and continues within 24 hours. Loratadin is metabolized in a liver with formation of an active metabolite of a dezkarboetoksiloratadin. The maximum concentration of a loratadin and its active metabolite in a blood plasma are reached in 1,3 – 2,5 hours after reception of one tablet of Lorageksal. Lorageksal does not cause drowsiness and does not influence psychomotor functions, attention, working capacity, mental capacities.

Indications to use:

For adults and children is more senior than two years Lorageksal is applied:
- for treatment of seasonal and year-round rhinitises, conjunctivitis, a pollinosis, a small tortoiseshell, a Quincke's edema, pseudo-allergic reactions, a pruritic dermatosis, allergic reactions to stings of insects.

Route of administration and doses:

It is applied inside. To adults and children 12 years are more senior: on 10 mg of Lorageksal (1 tablet) once a day. A daily dose – 10 mg. To children from 2nd to 12 years – on 5 mg of Lorageksal (1/2 tablets) once a day. A daily dose – 5 mg. To children with body weight more than 30 kg – on 10 mg of Lorageksal (1 tablet) once a day. A daily dose – 10 mg.

Features of use:

Patients with disturbances of functions of a liver Lorageksal need to appoint in an initial dose 5 mg/days in connection with possible disturbance of clearance of a loratadin.

It is not recommended to children up to 2 years.

Side effects:

Seldom – dryness in a mouth, nausea, vomiting, gastritis, an abnormal liver function, a headache, increased fatigue, excitability (at children), dizziness, cough, tachycardia, allergic reactions. In some cases – an alopecia.

Interaction with other medicines:

When using a loratadin in terapevtichesy doses its interaction with alcohol is not revealed. Erythromycin, Cimetidinum, кетоконазол at combined use with doratadiny increase concentration of a loratadin in a blood plasma, without causing clinical manifestations and without influencing an ECG.

Contraindications:

Hypersensitivity to any of drug components.

Precautionary measures:

Patients with disturbances of functions of a liver Lorageksal need to appoint in an initial dose 5 mg a day in connection with possible disturbance of clearance of a loratadin.
It is not recommended to children up to 2 years.

Pregnancy and lactation: it is necessary to refrain from Lorageksal's use at pregnancy and a lactation.

Overdose:

Overdose symptoms: drowsiness, tachycardia, headache. In case of overdose it is necessary to see a doctor and to take measures to removal of drug from zheludochno – an intestinal path and to decrease in absorption.

Storage conditions:

To store at a temperature not over 25º C in the place, unavailable to children!

Issue conditions:

Without recipe

Packaging:

Tablets, content are 10 mg of a loratadin (0,01g) on 7 or 10 tablets in the blister; on 1, 2, 3 or 5 blisters with the application instruction in cardboard packaging.