Gastratsid

General characteristics. Structure:

Active agents:
Aluminum hydroxide       of 400,00 mg
Magnesium hydroxide           of 400,00 mg

Excipients: Mannitolum, sodium saccharinate, sucrose, starch corn, sorbitol, aromatic mint additive, magnesium stearate.

Pharmacological properties:

Neutralizes free hydrochloric acid in a stomach that leads to reduction of the digesting activity of a gastric juice. Does not cause secondary hypersecretion of a gastric juice. Has the adsorbing and enveloping effect, reduces influence of disturbing factors on a mucous membrane of a stomach.

Indications to use:

- A peptic ulcer of a stomach and duodenum in an aggravation phase;
- Acute gastritis, chronic gastritis with the increased and normal secretory function in an aggravation phase, a duodenitis, enteritis;
- Hernia of an esophageal opening of a diaphragm, reflux esophagitis;
- Discomfort and pains in epigastriums at an error in a diet, after drug intake, the use of coffee, nicotine, alcohol;
- Preventively at treatment by glucocorticosteroids and non-steroidal anti-inflammatory drugs.

Route of administration and doses:

Inside. Tablets should be chewed or held in a mouth to a full rassasyvaniye.
To adults and children is more senior than 15-year age: on 1-2 tablets 4 times a day in 1 hour after food and in the evening before going to bed or at emergence of discomfort, pains in epigastriums, heartburn. The maximum daily dose – 12 tablets. To children from 10 to 15 years appoint a half of the recommended dose for adults.
For prevention - on 1 tablet in 15 minutes prior to drug intake, irritating mucous membrane of a gullet, a stomach and a duodenum.
Duration of treatment should not exceed 15-20 days.

Features of use:

The interval between Gastratsid's reception and other medicines has to make 1-2 hours.
At more prolonged use (more than 20 days) regular medical control is necessary. Drug contains sorbitol which is contraindicated at inborn intolerance of fructose.

Control of motor transport and work with mechanisms: does not exert impact on ability of driving and work with mechanisms.

Side effects:

Lock, nausea, vomiting, stomach spasms, change of flavoring feelings, gipermagniyemiya, hypophosphatemia, hypocalcemia, hypercalcuria, osteomalacy, osteoporosis, giperalyuminiyemiya, encephalopathy, nephrocalcinosis, renal failure, allergic reactions. Patients with the accompanying renal failure have a thirst, a lowering of arterial pressure, a hyporeflexia.

Interaction with other medicines:

Can absorb some medicines, reducing, thus, their absorption. Reduces and slows down absorption of digoxin, indometacin, salicylates, Chlorpromazinum, Phenytoinum, H2-gistaminoblokatorov, beta adrenoblockers, a diflunizal, an isoniazid, antibiotics of a tetracycline row, hinolon (ciprofloxacin, norfloxacin, an ofloksatsin, an enoksatsin, a grepofloksatsin, etc.), azithromycin, a tsefpodoksim, a pivampitsillin, rifampicin, indirect anticoagulants, barbiturates, a feksofenadin, Dipiridamolum, a zaltsitabin, bile acids – chenodeoxycholic and ursodeoksikholevy, Penicillaminum, iron preparations and lithium, quinidine, a lansoprazol, a meksiletin, a ketokonazol.

At a concomitant use with kishechnorastvorimy drugs a superalkalinity of a gastric juice can lead to the accelerated disturbance of a cover and cause irritation of a stomach and duodenum.

M-holinoblokatory, slowing down gastric emptying, strengthen and extend effect of drug.

Contraindications:

Hypersensitivity to drug components, intolerance of fructose, a hypophosphatemia, the expressed renal failure, Alzheimer's disease, children's age up to 10 years.

Pregnancy and period of a lactation: during pregnancy drug should be accepted under observation of the doctor and no more than 3 days. It is necessary to avoid use for nursing mothers.

Overdose:

Symptoms: at long reception of high doses emergence of heavy locks, drowsiness, a gipermagniyemiya are possible formation of stones in kidneys. Also signs of a metabolic alkalosis can be observed: change of mood, numbness or muscle pain, nervousness and bystry fatigue, unpleasant flavoring feelings.

Treatment: it is necessary to take measures for bystry removal of drug at once - to wash out a stomach, to cause vomiting, to accept absorbent carbon.

Storage conditions:

At a temperature not above 25 °C, in the dry, protected from light place.
To store in the place, unavailable to children!

Issue conditions:

Without recipe

Packaging:

For round tablets: on 10 tablets in the PVC/Al blister or a strip of Al/Al; on 1, 2, 3, 4, 5 blisters or strips in a cardboard pack with the application instruction.

For square tablets: on 4, 6, 8 tablets in the PVC/Al blister or a strip of Al/Al; on 1, 2, 3, 4, 5 blisters or strips in a cardboard pack with the application instruction.