Dibazolum

General characteristics. Structure:

Active agent - Bendazolum (Dibazolum) of 20 mg.

Excipients: sugar, starch, silicon dioxide, calcium stearate.

Pharmacological properties:

Has hypotensive, vasodilating effect, stimulates function of a spinal cord, has the moderate immunostimulating activity. Has direct spasmolytic effect on unstriated muscles of blood vessels and internals. Facilitates synoptic transfer in a spinal cord. The immunostimulating activity is connected with regulation of a ratio of concentration of tsGMF and tsAMF in immune cells (increases the maintenance of tsGMF) that leads to proliferation of mature sensibilized T - and V-lymphocytes, secretion by them of factors of mutual regulation, cooperative reaction and activation of final effector function of cells.

Possesses short (2-3 h) and moderate hypotensive effect, it is well transferred.

(Short) of brain vessels causes expansion and therefore it is especially shown at the forms of arterial hypertension caused by a chronic hypoxia of a brain because of local disturbances of blood circulation (a sclerosis of cerebral arteries).

Indications to use:

- hypertensive crisis;

- aggravation of a course of arterial hypertension;

- spasm of smooth muscles of internals (including stomach, intestines);

- residual phenomena of poliomyelitis, flaccid paralysis of a facial nerve.

Route of administration and doses:

Inside, in 2 hours prior to food or in 2 hours after food. Accept 1-2 tablets 2-3 times a day within 3-4 weeks or shorter courses. At treatment of nervous diseases - the adult in a dose of 5 mg of 1 times a day or every other day within 5-10 days, in 3-4 weeks the course of treatment is repeated. Further courses are conducted with breaks of 1-2 months.

At diseases of a nervous system at children: till 1 year — 1 mg, 1–3 years — 2 mg, 4–8 years — 3 mg, are more senior than 12 years — 5 mg.

Features of use:

It is not recommended to appoint for prolonged treatment of arterial hypertension, especially to patients of advanced age.

Prolonged use during pregnancy is not recommended. In the period of a lactation it is necessary to apply with care.

Side effects:

- allergic reactions;

- at use in high doses – feeling of heat, increase sweating, dizziness, nausea, a headache.

Interaction with other medicines:

Drug can be used in combination with other antihypertensives (Reserpinum, hypothiazid).

Contraindications:

Hypersensitivity to Bendazolum.

Overdose:

It is not revealed.

Storage conditions:

To store in the dry, protected from light place at a temperature not above 30 °C.

To store in the place, unavailable to children!

Issue conditions:

Without recipe

Packaging:

Tablets in a blister strip packaging on 10 pieces.

Planimetric packagings place in boxes from a cardboard together with the application instruction in the state and Russian languages.