Inspiron syrup

General characteristics. Structure:

Active ingredient: фенспирид; 5 ml of syrup contain fenspirida a hydrochloride 10 mg;

Excipients: methylparaben (Е 218), пропилпарагидроксибензоат (Е 216), potassium sorbate, aroma honey - a linden, a glycyrrhiza root extract, vanillin, glycerin, sodium saccharin, sugar, the water purified.

Pharmacological properties:

Pharmacodynamics. Inspiron shows antibronkhokonstriktorn and antiinflammatory properties. фенспирид:

- Blocks H1 - histamine receptors, has antihistaminic, spasmolytic effect on smooth muscles of bronchial tubes and prevents edematization, reduces mucifying from a nose and quantity of a bronchial secret

- Has antiinflammatory effect that is caused by braking of education and secretion of factors of an inflammation (cytokines, TNF - a, derivatives of arachidonic acid, prostaglandins, leukotrienes, thromboxane, free radicals);

- Inhibits a1 - adrenoceptors which stimulate secretion of viscous slime.

Pharmacokinetics. Concentration in a blood plasma is maximum it is reached, on average, in 2,3-2,5 hours (a limit of fluctuation of 0,5-8 hours). An elimination half-life - 12 hours. It is excreted from an organism preferential with urine.

Pharmaceutical characteristics.

The main physics - chemical properties: colourless or with a yellowish shade liquid with a specific smell. Easy opalescence is allowed.

Indications to use:

- Treatment of acute and chronic inflammatory processes the ENT SPECIALIST - bodies and respiratory tracts (otitis, sinusitis, rhinitis, a nasopharyngitis, tracheitis, rinotrakheobronkhit, bronchitis), as a part of complex therapy of bronchial asthma;

- Sezonny both year-round allergic rhinitis and other displays of an allergy from respiratory system and the ENT SPECIALIST - bodies;

- Respiratory displays of measles, flu;

- Symptomatic treatment of whooping cough.

Route of administration and doses:

For oral administration. Apply before food, previously to shake up bottle contents. The daily dose should be divided into 2-3 receptions.

To children aged from the birth to 14 rokivrekomendovan the daily dose makes 4 mg/kg of body weight. Drug can be added to a small bottle with baby food.

The recommended daily dose for children with body weight to 10 kg - 10-20 ml of syrup (2-4 teaspoons), for дитейз weight tila10 - 45 kg-30 - 90 ml of syrup (2-6 tablespoons).

The recommended daily dose for adults and children is more senior than 14 years of-75 - 90 ml of syrup (5-6 tablespoons). For use for adults use of the tableted medicines of a fenspirid is perhaps more reasonable.

Duration of treatment is defined by the doctor and depends on indications to use and courses of a disease. The minimum course of treatment of acute states - 7-10 days, chronicities - 2-6 months.

Features of use:

Refined sugar is a part of drug (3 g in one teaspoon) therefore it is necessary to be careful at Inspiron's use for the patients who are on a diet with the low content of sugar and also in the presence of a diabetes mellitus.

Treatment by drug does not replace an antibioticotherapia.

Ability to influence speed of response at control of motor transport or work with other mechanisms. Does not influence.

Side effects:

Usually Inspiron is well had. Possible side reactions:

allergic reactions: very seldom - an erythema, rash, a small tortoiseshell, the fixed pigmental erythema, a Quincke's edema.

from a digestive tract: digestive disturbances, nausea, vomiting, stomach ache;

from outside warmly - vascular system: in isolated cases - the sinus tachycardia disappearing at a dose decline.

others: drowsiness.

Interaction with other medicines:

It is not revealed.

Contraindications:

Hypersensitivity to a fenspirid of a hydrochloride and/or to other components of drug;
inborn intolerance of fructose, sprue of glucose and galactose, deficit of sucrose;
pregnancy, feeding period breast.

Overdose:

At overdose drowsiness, excitement, nausea, vomiting, sinus tachycardia are possible.

Treatment: it is necessary to wash out a stomach, to carry out monitoring of an ECG. Symptomatic therapy.

Use during pregnancy or feeding груддю. Zastosuvannya of drug during pregnancy contraindicated. In need of use of drug in the period of a lactation feeding by a breast should be stopped.

Children. Drug is used in pediatric practice.

Storage conditions:

Period of validity. 2 years. A period of validity after packaging opening - 1 month. To store in the place, unavailable to children, in original packaging at a temperature not over 25 ºС. Not to freeze.

Issue conditions:

According to the recipe

Packaging:

On 150 ml in the bottles enclosed in packs with a spoon measured.