Flyukomp

General characteristics. Structure:

Active ingredients: 325 mg or 650 mg of paracetamol, 20 mg of pheniramine of a maleate, 10 mg of Phenylephrinum of a hydrochloride.

Excipients: citric acid, sodium hydrocitrate, dextrin, maltodextrin, sucrose (sugar), aspartame, fragrance ("lemon" or "orange"), dye ("quinolinic yellow" or "sunset").
 

Pharmacological properties:

Pharmacodynamics. The combined drug, has febrifugal, protivokognestivny, anesthetizing and antiallergic effects. Eliminates symptoms of "cold" (a hyperthermia, a fever, a headache, cold, a nose congestion, sneezing, muscle pains).

Paracetamol has febrifugal and analgeziruyushchy effect: reduces the pain syndrome which is observed at catarrhal states - a pharyngalgia, a headache, muscular and joint pain, reduces high temperature.

Phenylephrinum has vasoconstrictive effect - reduces hypostasis and a hyperemia of mucous membranes of upper parts of respiratory tracts and adnexal bosoms.

Pheniramine has antiallergic effect: eliminates an itch of eyes, a nose and throat, puffiness and a hyperemia of mucous membranes of a nasal cavity, a nasopharynx and adnexal bosoms of a nose, reduces exudative manifestations.

Indications to use:

Symptomatic treatment of a SARS and other "catarrhal" diseases, including flu.

Route of administration and doses:

Inside. To adults and children 12 years are more senior - to dissolve contents of one bag in 1 glass of boiled hot water. It is possible to add sugar to taste. To use hot. It is possible to accept a repeated dose every 4 hour (no more than three doses during 24 h).

Use is possible at any time, but the best effect accords administration of drug before going to bed, for the night. Treatment should not exceed 3 days (then drug is cancelled, irrespective of existence of consultation of the doctor).

Features of use:

During treatment it is necessary to abstain from the ethanol use (possibly development of a hepatotoxic action), driving of motor transport and occupations other potentially dangerous types of activity demanding the increased concentration of attention and speed of psychomotor reactions.

Side effects:

Nausea, vomiting, epigastric pain, drowsiness, feeling of fatigue, reduction in the rate of psychomotor reactions, hyperexcitability, heart consciousness, increase in arterial pressure, dizziness, sleep disorder, mydriasis, accommodation paresis, increase in intraocular pressure, ischuria, allergic reactions, anemia, thrombocytopenia, leukopenia, agranulocytosis are possible dryness in a mouth, at long reception of high doses — vozmozhnygepatotoksichesky and nephrotoxic action, hemolitic anemia, a methemoglobinemia, a pancytopenia.

Interaction with other medicines:

It is not compatible to monoaminooxidase inhibitors. Barbiturates, Phenytoinum, carbamazepine, rifampicin, a zidovudine and other inductors of microsomal enzymes of a liver increase risk of hepatotoxic effect of paracetamol.

Strengthens effect of sedatives, ethanol. Ethanol strengthens sedative effect of pheniramine.

Antidepressants, protivoparkinsonichesky and antipsychotic means, fenotiazinovy derivatives increase risk of development of an ischuria, dryness in a mouth.

Contraindications:

Hypersensitivity to drug components, pregnancy, the lactation period, children's age up to 12 years, deficit of invertase/isomaltase, intolerance of fructose, glyukozo-galaktozny malabsorption, a fenilketonuriya.

With care. Arterial hypertension, diabetes mellitus, closed-angle glaucoma, serious illness of a liver or kidneys, prostate hyperplasia, deficit glyukozo-6-fosfatdegidrogenazy.

Overdose:

Symptoms: pallor of integuments, anorexia, nausea, vomiting, pains in epigastric area; hepatotoxic and nephrotoxic action, in hard cases - a liver failure, encephalopathy and a coma.

Treatment: a gastric lavage, purpose of absorbent carbon, symptomatic therapy, introduction of donators of SH-group and predecessors of synthesis of glutathione - methionine in 8-9 h after overdose and N-Acetylcysteinum in 12 h.

Storage conditions:

In the dry, protected from light place at a temperature not above 25 °C. To store in the place, unavailable to children. A period of validity - 2 years. Not to use after the expiry date specified on packaging.

Issue conditions:

Without recipe

Packaging:

Powder for preparation of solution for intake (lemon, orange). On 2,5 g (at a dosage of 325 mg + 20 mg + 10 mg) or on 5 g (at a dosage of 650 mg + 20 mg + 10 mg) in the bag thermowelded from material film combined or from the material combined multilayer or from a foil of kashirovanny packaging. On 5, 10, 20, 30, 40 or 50 bags together with the instruction on a medical use place in a pack from a cardboard.