Piratsetam-Darnitsa, the tab. п / about 0.2 g No. 60

General characteristics. Structure:

International and chemical name: piracetam; 2-oxo-pyrrolidinyl-1-acetamide - a synthetic analog of y-aminobutyric acid;
main physical and chemical properties: tablets, coated, yellow color;
structure: piracetam - 0,2 g;
excipients: calcium stearate, potato starch, polyvinylpirrolidone, magnesium carbonate the main.

Pharmacological properties:

Piratsetam-Darnitsa strengthens dopamine synthesis in a brain, increases the maintenance of noradrenaline, increases also quantity of acetylcholine at the synoptic level and density of holinoretseptor. It is impossible to exclude GAMK-ergichesky elements from effect of drug in spite of the fact that it does not turn into GAMK. Drug positively influences exchange processes and blood circulation of a brain, stimulates oxidation-reduction processes, increases glucose utilization, improves a regional blood stream in ischemic sites of a brain, increases energy potential of an organism with the participation of ATP and adenylatecyclase. Optimization of power processes promotes increase in resistance of TsNS to a hypoxia and various toxic factors. Piratsetam-Darnitsa improves integrative activity of a brain, promotes memory consolidation, improves training processes.

Pharmacokinetics. Piracetam after intake is well soaked up, getting into bodies and fabrics, including a brain. It is removed by kidneys practically in a nemetabolizirovanny form.

Indications to use:

Piratsetam-Darnitsa appoint to adults and children at the diseases of a nervous system which are especially caused by vascular disorders, inversions of exchange processes of a brain (including people of advanced and senile age). At neurologic patients drug is appointed at brain atherosclerosis, vascular parkinsonism, other pathological processes with the phenomena of chronic cerebral and vascular insufficiency, with disturbance of memory, attention, the speech, dizziness, at changes of cerebral circulation, coma and subcomas owing to injuries of a brain and intoxications. Apply at diseases of a nervous system with decrease intellectual мнестических functions and disturbances of the emotional and strong-willed sphere. 
In psychiatric practice apply at neurotic and astenoadinamichesky depressions with dominance of signs of an adynamia, asthenic, senesto-hypochiondrial disturbances, ideatorny block, at vyaloapatichesky defective states at schizophrenia, at psychoorganic syndromes of a different etiology, senile and atrophic processes, in complex therapy of mental diseases. Appoint in complex therapy of senile dementias, including Alzheimer's disease.
In pediatrics of Piratsetam-Darnitsa apply at tserebrostenichesky, encephalopathic disturbances, dysmnesias, intellectual insufficiency, etc.
Piratsetam-Darnitsa use for stopping of abstinent, predeliriozny and delirious states at alcoholism, drug addiction, in cases of an acute alcoholic poisoning, morphine, barbiturates, etc. At an alcoholism of Piratsetam-Darnitsa appoint for reduction of the phenomena of an adynamy, intellectual мнестических and other disturbances of mental activity. It is reasonable to use drug at acute virus neuroinfections for reduction of ischemia and a hypoxia of a brain. Anti-hypoxemic influence of drug should be considered in complex therapy of a myocardial infarction.

Route of administration and doses:

Piratsetam-Darnitsa appoint inside to food, since 1,2 g (0,4 g 3 times a day) and raising a dose to 2,4 g (sometimes to 3,2 g and more) in days. The therapeutic effect usually occurs in 2-3 weeks from an initiation of treatment. Further the dose is lowered till 1,2 - 1,6 (0,4 g 3 - 4 times a day).
To children appoint in the form of tablets of yellow color, coated: up to 5 years - on 0,2 g 3 times a day (to 0,8 g a day); from 5 to 16 years - on 0,4 g 3 times a day.
The maximum daily dose - 1,8 g.
The course of treatment drug makes from 2-3 weeks to 2-6 months and if necessary .povtoryatsya in 6-8 weeks.

Features of use:

Purpose of Piratsetama-Darnitsa can be combined with psychotropic, cardiovascular and many other drugs. There are data on strengthening by drug of effect of antidepressants.

Side effects:

Piratsetam-Darnitsa it is usually well transferred to force of practical non-toxicity. At some patients the acrimony, concern, a sleep disorder, the dispeptic phenomena are possible, patients of advanced age can have a sharpening of coronary insufficiency (it is necessary to reduce a dose or to stop administration of drug). Allergic reactions, manifestations of individual intolerance are not excluded.

Contraindications:

Acute renal failure; do not appoint to the children having diabetes and with existence in the anamnesis of data on the allergic reactions connected with the use of fruit juice, essences. Children are also not recommended to appoint drug aged till 1 year.

Storage conditions:

To store in the dry, protected from light place. A period of validity - 5 years.

Issue conditions:

According to the recipe

Packaging:

Tablets on 0,2 g, coated, on 10 pieces in blister strip packagings.