Potassium orotat-OBL

General characteristics. Structure:

Active ingredient: 500 mg of orotovy acid in 1 tablet.

Excipients: lactose (sugar milk), potato starch, edible gelatin, stearic acid.

Pharmacological properties:

Pharmacodynamics. Nonsteroid anabolic drug. Stimulates synthesis of nucleic acids, increases appetite, possesses diuretic, regenerating properties. Improves portability of cardiac glycosides, strengthens reparative and regenerative processes in fabrics; has a promoting effect on a metabolism, strengthens formation of albumine in a liver (especially in the conditions of a long hypoxia), promotes fixing of Mg2 + on ATP in a cell and to manifestation of its action.

Pharmacokinetics. It is absorbed in a GIT (10% of the accepted dose). Turns in a liver into orotidin-5-phosphate. It is removed by kidneys (30% in the form of various metabolites).

Indications to use:

Potassium оротат treats group of the means stimulating exchange processes. As supportive application at the diseases of a liver and bilious ways (caused by acute and chronic intoxication, except for organic lesions of a liver and biliary tract): as a part of a combination therapy of chronic heart failure and disturbances of a heart rhythm; an alimentary and alimentary and infectious hypotrophy at children.

Route of administration and doses:

Pill of potassium of an orotat should be taken inside in 1 hour prior to food or in 4 hours after food. The adult on 250-500 mg (1/2-1 tablet) 2-3 times a day. The course of treatment lasts on average 20-30 days. If necessary treatment can be repeated in 1 month. In exceptional cases it is possible to increase a dose of adults to 3 g a day.

To children - on 10-20 mg/kg of body weight the day divided into 3-4 receptions (for example, if the body weight of the child of 25 kg, then the resolved dose – from 25 x 10 = 250 mg (1/2 tablets) to 25 x 20 = 500 mg (1 tablet the day divided into 3-4 receptions).

Course of treatment of 3-5 weeks. At preservation of symptoms of a disease consult with the doctor.

Features of use:

It is possible to apply a long time.

Side effects:

Usually potassium оротат it is well transferred. In some cases there can be allergic skin reactions which disappear after treatment interruption. Potassium оротат can cause easy digestive disturbances also. At use in high doses against the background of a low-proteinaceous diet development of dystrophy of a liver is possible.

At emergence of side effects consult with the doctor.

Interaction with other medicines:

Potassium оротат reduces toxicity of cardiac glycosides a little.

The effect of potassium of an orotat increases at its combination with magnesium drugs.

The knitting and enveloping means can reduce several absorption of potassium of an orotat in digestive tract.

Contraindications:

Potassium оротат cannot be applied at hypersensitivity to any of drug components; acute and chronic organic lesion of a liver.

Overdose:

Data on overdose of tablets of potassium of an orotat are absent.

Storage conditions:

In the dry, protected from light place at a temperature not above 25 °C. To store in the place, unavailable to children. A period of validity - 3 years. Not to use after the expiry date specified on packaging.

Issue conditions:

Without recipe

Packaging:

Form of release of the Tablet on 500 mg. On 10 tablets in a blister strip packaging from a film of the polyvinyl chloride and printing aluminum foil varnished. 1, 2 or 3 blister strip packagings together with the application instruction place in a pack from a cardboard.