Валокордин®

General characteristics. Structure:

Active agents: 18,4 mg of phenobarbital, 18,4 mg of ethyl ether of α-bromizovalerianovy acid.

Excipients: mint oil — 1,29 mg; hop oil — 0,18 mg; ethanol of 96% — 469,75 mg; the water purified — 411,97 mg.

Pharmacological properties:

Pharmacokinetics. Valocordin - the combined medicine which therapeutic effect is caused by pharmacological properties of the components which are its part.

Phenobarbital possesses sedative and vazodilatiruyushchy action, and also has soft somnolent effect. Promotes decrease in excitement of TsNS and facilitates approach of a natural dream.

Etilbromizovalerianat has sedative, somnolent and spasmolytic effect. Oil of a peppermint has reflex vasodilating and spasmolytic activity.

Indications to use:

— functional frustration of cardiovascular system (including cardialgia, sinus tachycardia);

— the neurosises which are followed by irritability, concern, fear;

— sleeplessness (backfilling difficulty);

— the conditions of excitement which are followed by the expressed vegetative reactions.

Route of administration and doses:

Valocordin is accepted inside, to food, with a small amount of liquid. The dosage is established individually. The adult appoint usually till 15-20 drops of 3 times/days. At the broken backfilling it is possible to increase a dose to 30 drops.

To children appoint at the rate of 1 drop to a year of life of the child and depending on a clinical picture of a disease.

Duration of use of drug is established individually by the doctor.

Features of use:

Drug contains 55 volume % of ethanol and phenobarbital therefore Valokordin® even at the correct use can weaken ability of patients quickly to react in certain situations as, for example, at stay on the street or at service of cars. It is especially strongly expressed at a concomitant use of alcohol.

At prolonged use of drug formation of medicinal dependence is possible; accumulation of bromine in an organism and development of poisoning with it is possible.

Use at pregnancy and feeding by a breast. It is contraindicated. In need of purpose of drug in the period of a lactation it is necessary to resolve an issue of the breastfeeding termination.

Use at abnormal liver functions. It is contraindicated at the expressed abnormal liver functions.

Use at renal failures. It is contraindicated at the expressed renal failures.

Use for children. To children appoint at the rate of 1 drop to a year of life of the child and depending on a clinical picture of a disease.

Side effects:

Валокордин®, as a rule, it is well transferred even at prolonged use.

In some cases, drowsiness and slight dizziness can be observed in the afternoon.

At prolonged use of high doses development of chronic poisoning with bromine which manifestations happen is possible: the depressive mood, apathy, rhinitis, konjyuktivit, hemorrhagic diathesis, a lack of coordination of movements.

At manifestation of any side (unusual) effects which are not reflected vinstruktion it is necessary to report about them to the attending physician.

Interaction with other medicines:

At simultaneous use of Valocordin with sedatives strengthening of effect is noted.

Simultaneous use with neuroleptics and tranquilizers strengthens, and with TsNS stimulators - weakens action of each of drug components.

Alcohol strengthens effects of Valocordin and can increase its toxicity.

Existence in composition of Valocordin of phenobarbital can induce liver enzymes, and it does undesirable its simultaneous use with drugs which are metabolized in a liver as their concentration, and respectively efficiency will decrease as a result of more accelerated metabolism (indirect anticoagulants, antibiotics, streptocides).

Phenobarbital weakens action of derivatives of coumarin, GKS, griseofulvin, peroral contraceptive means.

Contraindications:

— the expressed renal failures and/or a liver;

— pregnancy,

— lactation period;

— hypersensitivity to any of drug components.

Overdose:

Symptoms: at slight and medium-weight intoxication drowsiness, dizziness, psychomotor disturbances is observed. In hard cases - a coma, decrease in the ABP, breath disturbance, tachycardia, a vascular collapse, decrease in peripheral reflexes.

Treatment: to wash out a stomach, to accept absorbent carbon.

Storage conditions:

In original packaging at a temperature not above 25 °C.

Issue conditions:

Without recipe

Packaging:

Drops for intake. On 20 or 50 ml in bottles of brown glass with a dropper. Each bottle dropper is placed in a pack cardboard.