Elastic pseudoxanthoma
Contents:
Description:
Elastic pseudoxanthoma - the hereditary disease of connecting fabric affecting skin, eyes and blood vessels.
At an elastic pseudoxanthoma mainly elastic fibers which provide distensibility and elasticity of fabrics are surprised. The forecast depends on that, the disease and what arteries are affected is how heavy. Death owing to development of complications usually comes between 30 and 70 years.
Reasons of an elastic pseudoxanthoma:
The elastic pseudoxanthoma is a hereditary disease with an autosomal and dominant or autosomal and recessive mode of inheritance.
The elastic pseudoxanthoma is provoked:
Pregnancy.
Endocrine disturbances.
Diabetes mellitus.
Puberty.
Injuries.
Toxoplasmosis.
Symptoms of an elastic pseudoxanthoma:
Skin of a neck, axillary areas, groin and area around a navel thick, has a set of folds, rigid. Yellowish dense nodes give to the patient's skin similarity to leather of a chicken. Changes in a retina of eyes can lead to the expressed decrease in sight and even a blindness.
Arteries are narrowed; result thorax pain and
the alternating lameness (the onychalgia during loading connected with insufficient blood supply). There can be nasal bleedings and bleedings in a brain, a uterus and intestines. Increase in arterial pressure is characteristic.
Consolidation of skin at an elastic pseudoxanthoma
Diagnosis:
Clinical picture of an elastic pseudoxanthoma very characteristic. The skin biopsy is necessary for confirmation of the diagnosis. Also consultation of the oculist who finds angioidny strips on an eyeground is appointed.
For inspection of the struck vessels carrying out an angiography is possible. The X-ray analysis reveals calcification of arteries of the lower extremities.
Treatment of an elastic pseudoxanthoma:
Principles of treatment of an elastic pseudoxanthoma:
Correction of endocrine disturbances.
Prevention of injuries.
Restriction of non-steroidal anti-inflammatory drugs and anticoagulants (as development of bleeding is dangerous).
Vitamins A, E, Rutinum, ascorbic acid.
For delay of damage of eyes it is used laser or photocoagulation.
