Iodine of 5%

General characteristics. Structure:

Active ingredient: 50 g of iodine, 20 g of potassium of iodide.

Excipients: alcohol of 95%, the water purified.

Pharmacological properties:

Pharmacodynamics. Antiseptic agent. The main active ingredient is the molecular iodine having antiseptic property. When drawing iodine has resorptive effect on the extensive surfaces of skin: actively influences a metabolism, participates in thyroxine synthesis, possesses proteolytic action. Alcohol – the high-molecular connection which is slowing down removal of iodine and reducing it irritant action by fabrics.

Has bactericidal effect, as on gram-positive flora (is the most active – on a streptococcus and an intestinal shelf), and also on pathogenic fungi and yeast. More persistent flora is staphylococcus, however at prolonged use of drug in 80% of cases it disappears. The pyocyanic stick is steady. Drug is a little toxic.

Pharmacokinetics. At contact with skin for 30% turns into iodides, and other part gets into fabrics and bodies, is selectively absorbed by a thyroid gland. It is allocated with kidneys (mainly), intestines, sweat glands, with milk in the period of a lactation.

Indications to use:

Inflammatory and infectious diseases of skin, graze, cuts, microtraumas, wounds; miositis, neuralgia, inflammatory infiltrates; disinfection of a surgery field (before - and postoperative processing of a surgery field, carrying out injections, punctures, catheterizations), edges of wounds, the surgeon's hands.

Route of administration and doses:

Outwardly, grease affected areas of skin. When processing a surgery field skin is twice wiped with the sterile gauze tampon moistened in solution. The general time of processing – 4-6 minutes.

Features of use:

At combined use with yellow mercury ointment formation of mercury of the iodide possessing the cauterizing action is possible.

Side effects:

Irritation of skin, at prolonged use on extensive wound surfaces – an iodism (rhinitis, urticaria, a Quincke's edema, hypersalivation, dacryagogue, acne rash).

Interaction with other medicines:

Pharmaceutical it is incompatible with essential oils, ammonia solutions, white sedimentary mercury (explosive mix is formed).

Alkaline or acid medium, presence of fat, pus, blood weakens antiseptic activity.

Contraindications:

Hypersensitivity.

Storage conditions:

In the place unavailable to children protected from light, at a temperature not below 0 °C. A period of validity - 3 years when packaging in bottles and large bottles, 1 year when packaging in a pharmograf. Not to use after the term specified on packaging.

Issue conditions:

Without recipe

Packaging:

On 10 ml and 25 ml in bottles from glass melt, on 10 ml in bottles from dark glass, on 3 ml and 5 ml in the device polymeric with a firm porous core – a pharmograf, on 18 kg in bottles glass. Each bottle or a pharmograf with the application instruction place in a pack.