Kofan instant

General characteristics. Structure:

Active ingredient: paracetamol of 200 mg, propyphenazone of 200 mg, caffeine of 50 mg.

Description. Tablets of white color, round.

Pharmacological properties:

The combined drug which effect is defined by the components which are its part.

Caffeine renders psychogogic (stimulates the psychomotor centers of a brain), analeptical action, strengthens effect of analgetics, eliminates drowsiness and feeling of fatigue, increases physical and intellectual effeciency.

Paracetamol and propyphenazone have analgeziruyushchy and febrifugal effect.

Indications to use:

— pain syndrome of moderate expressiveness: headache, dentagra, mialgiya, posttraumatic pain;

— feverish syndrome: catarrhal diseases, flu.

Route of administration and doses:

Inside to adults and children 12 years - on 1 tablets to 4 times / are more senior, washing down with a small amount of water.

Features of use:

The excessive use of kofeinsoderzhashchy products (coffee, tea) against the background of treatment can cause overdose symptoms.

At long (more than 1 week) treatment control of a picture of peripheral blood and a functional condition of a liver is necessary.

Without consultation of the doctor accept no more than 3 days at treatment of a feverish syndrome and no more than 5 days - at a pain syndrome.

Can change results of analyses of a drug test of athletes.

Complicates establishment of the diagnosis at a symptom complex "acute abdomen".

The patients having atopic bronchial asthma, pollinoses have an increased risk of development of allergic reactions.

During treatment it is necessary to refuse the ethanol use (increase in risk of development of a hepatotoxic).

Side effects:

Nausea, increase in the ABP, sleeplessness, allergic reactions (dermahemia, skin rash, bronchospasm, rhinorrhea).

Interaction with other medicines:

Paracetamol raises time of removal of chloramphenicol by 5 times.

At repeated reception paracetamol can strengthen effect of indirect anticoagulants (Dicumarinum derivatives).

Caffeine accelerates ergotamine absorption.

The concomitant use of paracetamol and ethanol increases risk of development of hepatotoxic effects.

Barbiturates, rifampicin, Salicylamidums, anticonvulsant medicines and other stimulators of a microsomal oxidation promote formation of the toxic metabolites of paracetamol influencing function of a liver.

Metoclopramidum accelerates paracetamol absorption.

Contraindications:

— hypersensitivity;

— heavy liver and/or renal failure;

— deficit glyukozo-6-fosfatdegidrogenazy;

— oppression of a marrowy hemopoiesis (leukopenia, anemia, including hemolitic);

— acute hematoporphyria;

— bronchial asthma;

— the states which are followed by respiratory depression;

— intracranial hypertensia;

— acute myocardial infarction;

— arrhythmias;

— arterial hypertension;

— alcoholic intoxication, alcoholism;

— glaucoma;

— pregnancy;

— period of a lactation (breastfeeding);

— children's age (up to 12 years).

With care: a peptic ulcer of a stomach and a 12-perstny gut (in an aggravation stage), advanced age.

Use at pregnancy and feeding by a breast
It is contraindicated at pregnancy, in the period of a lactation.

Use at abnormal liver functions
It is contraindicated at a heavy liver failure.

Use at renal failures
It is contraindicated at a heavy renal failure.

Use for elderly patients
With care: advanced age.

Use for children
It is contraindicated at children's age up to 12 years.

Overdose:

Symptoms: vomiting, abdominal pain, ikterichnost of integuments, vision disorder, spasms, hyperexcitability, arrhythmias, drowsiness, loss of consciousness.

Issue conditions:

According to the recipe

Packaging:

10 - planimetric strip packagings (2) - packs cardboard.