Prostaplant
Producer: Dr. Willmar Schwabe GmbH & Co.KG. ("Doctor of Wilmar Schwab Gmbh & Co. KG") Germany
Code of automatic telephone exchange: G04CX02
Release form: Firm dosage forms. Capsules.
General characteristics. Structure:
Active ingredient: 320 mg of dry extract of fruits of a serenoa creeping (10-14.3:1) *.
Excipients: gelatin polysuccinate, глицерол, dye ferrous oxide black (E172), dye ferrous oxide yellow (E172), dye patent blue V (E131).
* extragent: ethanol of 90%.
Pharmacological properties:
Pharmacodynamics. The phytodrug applied at the functional disturbances of an urination connected with a benign hyperplasia of a prostate. Has anti-androgenic, antiinflammatory and antiedematous effect selectively on prostate gland tissues.
The mechanism of anti-androgenic action is caused by inhibition of activity 5 - alpha reductases (owing to what transformation of testosterone in dihydrotestosterone is broken). The Prostaplant interferes with formation of a dihydrotestosterone-receptor-complex, its penetration into a kernel of a cell and the subsequent induction of synthesis of protein. As a result of this action process of proliferative changes in prostate gland tissues is slowed down. The Prostaplant does not influence levels of testosterone, FSG and LG in a blood plasma at men.
Antiinflammatory and antiedematous effect of drug is caused by inhibition of enzymes - cyclooxygenases and 5-lipooksigenaza.
The Prostaplant reduces capillary permeability and vascular стаз, reduces hypostasis and an inflammation of a prostate, eliminating thus a compression on a neck of a bladder and an urethra, improving dynamics of urinary tract.
Use of drug promotes reduction of specific symptoms of a benign hyperplasia of a prostate (a dysuria, a pollakuriya, a nocturia, decrease in volume and force of an urination, incomplete bladder emptying, painful feelings and feeling of tension in a crotch at I and II stages of a disease).
The Prostaplant does not reduce a potentiality, does not exert impact on the level of the prostates specific antigens (PSA) in a blood plasma.
Pharmacokinetics. Effect of drug of Prostaplant is cumulative action of its components therefore carrying out kinetic researches is not possible.
Indications to use:
— disturbances of an urination at a benign hyperplasia of a prostate of I and II stages.
Route of administration and doses:
Appoint on 1 capsule of 1 times/days.
Capsules accept without chewing, washing down with a small amount of liquid. Duration of a course of treatment - not less than 3 months.
The optimum scheme and repeated courses of treatment are established and appointed by the doctor individually in each case on the basis of diagnostic inspection.
Features of use:
With care patients should appoint drug with gastrointestinal diseases in the anamnesis. Before use of drug it is necessary to be convinced that the disease has high-quality character.
Side effects:
From the alimentary system: seldom - nausea, heartburn, a gastralgia (especially at administration of drug on an empty stomach).
Others: allergic reactions are possible.
Interaction with other medicines:
Clinically significant medicinal interaction of drug of Prostaplant is not revealed.
Contraindications:
— hypersensitivity to drug components.
Overdose:
So far about cases of overdose of drug of Prostaplant it was not reported.
Storage conditions:
To store at a temperature from +15 °C to +25 °C, in the dry place. To store in the place, unavailable to children. Period of validity of 5 years. Not to use drug after the period of validity specified on packaging!
Issue conditions:
Without recipe
Packaging:
On 10 capsules in the blister or on 20 capsules in the blister. On 3 blisters (on 10 capsules), on 3 blisters (on 20 capsules) or on 6 blisters (on 20 capsules) in a cardboard pack.