Bisacodyl

General characteristics. Structure:

Active agent: bisacodyl — 5 mg.

Excipients (kernel): lactose (sugar milk) — 60 mg, potato starch — 10 mg, povidone (коллидон 25) — 3,8 mg, cellulose microcrystallic — 15 mg, calcium stearate — 0,6 mg, talc — 0,6 mg.

Excipients (cover): целлацефат (atsetilftaliltsellyuloza) — 2,75 mg, polysorbate (twin-80) — 0,9 mg, castor oil — 0,3 mg, titanium dioxide — 1,05 mg.

Pharmacological properties:

Purgative. Causes irritation of the receptor device of a gut, exerts direct impact on a mucous membrane of intestines, strengthening its peristaltics and increasing secretion of slime in a large intestine. Action comes in 6 hours, at reception before going to bed — in 8-12 hours.

Pharmacokinetics. It is not soaked up in intestines. Is pro-medicine, in the alkaline environment there is a hydrolysis to formation of the metabolite rendering irritant action on a mucous membrane of digestive tract.

Indications to use:

Hypotonic and atonic locks (including locks at elderly; locks after operations and childbirth). Regulation of a chair (hemorrhoids, proctitis, anal fissures). Preparation for surgeries, tool and X-ray inspections.

Route of administration and doses:

Inside. At the locks caused by hypotonia of a large intestine for regulation of a chair at hemorrhoids, a proctitis, proctal cracks to adults and children 14 years drug are more senior appoint 1-3 tablets (5-15 mg) to reception, to children at the age of 8-14 years on 1-2 tablets (5-10 mg), 3-7 years on 1 tablet (5 mg). Frequency of reception is 1 time a day for the night or in the morning in 30 minutes prior to food.
By preparation for surgeries, tool and X-ray inspections appoint 2 tablets to night one day before the research and on 2 tablets for the night on the eve of operation or a research.
Tablets need to be swallowed entirely, washing down with a small amount of liquid.

Features of use:

Not to apply for a long time (more than 10 days).

Side effects:

Intestinal colic, diarrhea (dehydration, disturbance of water and electrolytic exchange, muscular weakness, spasms, decrease in the ABP), abdominal pain, meteorism, allergic reactions.

Interaction with other medicines:

Combined use with antacids can lead to premature dissolution of its cover and irritation of a stomach and a 12-perstny gut. It is not recommended to accept along with milk and alkaline mineral water.

Contraindications:

Hypersensitivity, intestinal impassability, the restrained hernia, acute inflammatory diseases of abdominal organs, peritonitis, bleedings from digestive tract, a metrorrhagia, cystitis, spastic locks, an acute proctitis, acute hemorrhoids, children's age up to 3 years.
With CARE. Pregnancy, lactation period, liver and/or renal failure.

Overdose:

Symptoms: diarrhea, dehydration, disturbance of water and electrolytic balance, hypopotassemia, atony of a large intestine.
Treatment: symptomatic.

Storage conditions:

To store in the dry, protected from light place at a temperature not above 25 °C. To store in the place, unavailable to children.

Issue conditions:

Without recipe

Packaging:

The tablets covered with a kishechnorastvorimy cover of 5 mg. On 10, 30 tablets in a blister strip packaging from a film polyvinylchloride ache, the printing aluminum foil varnished. On 10, 20, 30, 40, 50 or 100 tablets in a container polymeric for medicines or a bottle from glass melt with the screwed plastic or aluminum covers.
One container (bottle) or 1, 2, 3, 4, 5, 6, 8 or 10 blister strip packagings together with the application instruction place in a pack from a cardboard.
On 5, 10 or 20 containers (bottles) or on 20, 40, 60, 80 and 100 blister strip packagings together with the corresponding number of application instructions place in a box from a cardboard (for hospitals).