Cesaria's syndrome
Contents:
Description:
Disease at which lymphocytes (a kind of leukocytes) become malignant (cancer) and affect skin.
Cesaria's syndrome is the started form of a fungoidny granuloma.
Symptoms of the Syndrome of Cesaria:
The preerythrodermic period of a syndrome of Cesaria can proceed differently. At the first option the disease can begin with emergence of disseminated rashes of erythematic and squamous or ekzemopodobny character which before development of an erythrosis can exist from several weeks to several years. At the second option of a current of a syndrome of Cesaria which is noted much more often process develops actively, on skin quickly there are centers of erythematic and infiltrative character which merge, causing for rather short time total damage of skin — an erythrosis. The period of the disseminated rashes preceding an erythrosis at such option of development of a disease is practically absent.
The erythrosis is the main clinical symptom of a disease. Color of the affected skin usually bright red or stagnant and cyanotic. Infiltration of skin, as a rule, has the expressed character owing to what skin looks rough, reinforced and hardly gathers pleated. Dryness and a peeling of skin are in a varying degree noted at all patients. In comparison with clinical symptoms of patients with an erythrodermic form of fungoid mycosis patients to Cesaria's syndrome more often and more have skin dyschromias in the form of hyperpegmentations of idepigmentation, a poikiloderma, giperkeratoza of palms and soles, alopecias, onikhodistrofiya, ectropion. In general clinical displays of these diseases are very similar.
The expressed lymphadenopathy is noted at all patients. The increased inguinal, femoral, axillary, kubitalny lymph nodes are palpated in the form of packages of a plotnoelastichesky consistence, are not soldered to surrounding fabrics, are painless. Gepato-and a splenomegaly decide at 25-30% of patients on Cesaria's syndrome.
The most typical subjective symptoms of a disease are the persistent itch of skin, burning and a pricking. The general state bolvny heavy, strong oznoba, the broken sweating, rises in temperature till 38-39 °, the expressed weakness, pathological deviations are noted from cardiovascular system.
Reasons of the Syndrome of Cesaria:
Cesaria's syndrome is leukemic option of fungoid mycosis, in particular the erythrodermic Hallopeu form. Proliferation in skin, and then in regional lymph nodes of atypical lymphocytes with mozgovidny kernels - the Cesaria's cells (CC) is the cornerstone of development of these diseases.
Treatment of the Syndrome of Cesaria:
There are several various ways of treatment of patients with the diagnosis Cesaria's syndrome. Some ways of treatment are standard (are applied now), and some new ways of treatment pass clinical test. Clinical testing is a research studying which purpose is improvement of a standard way of treatment or obtaining information on results of new ways of treatment of cancer patients. If clinical tests show that the new way of treatment is better, than standard, such way of treatment can become a standard way of treatment afterwards. At will patients can also take part in clinical tests. Only patients who did not undergo any treatment yet can take part in some clinical tests.
Photodynamic therapy
Photodynamic therapy – a way of cancer therapy which purpose is destruction of cancer cells. The principle of photodynamic therapy consists in use of medicine which becomes more active only at influence by the light radiation of a certain range or special laser radiation. Medicine is administered in a vein. Medicinal substance does not become more active until do not influence it radiation. Drug collects in cancer cells in bigger quantity, than in healthy full-fledged cells. Laser radiation, getting on skin, activates medicinal substance which destroys cancer cells. At photodynamic therapy there are insignificant damages of healthy fabrics. Patients who receive medical treatment for photodynamic therapy should stay less in the sun. At one type of photodynamic therapy to patients enter medicinal substance Psoralenum and then influence skin ultraviolet radiation. Such type of photodynamic therapy is called ultra-violet therapy with Psoralenum. Other type of photodynamic therapy is called extracorporal photochemotherapy. To patients enter medicinal substance and then from blood of the patient allocate some blood cells which subject to influence by the special ultraviolet radiation And then the irradiated blood cells are entered back into the patient's organism.
Radiation therapy:
Radiation therapy is a way of treatment of an oncological disease at which hard x-ray emission or other types of radiation radiations for prevention of growth of cancer cells or their destruction is used. There are two types of radiation therapy. External radiation therapy at which the special device focuses radiation in the field of a tumor. Internal radiation therapy at which the radioactive material which is hermetically packed in needles, capsules, cores or catheters is placed directly in or near a tumor.
In certain cases treatment of fungoidny granulomas and Cesaria's syndrome is performed with the help by radiation therapy by a bunch of electrons to all skin. At this type of radiation therapy all integument is affected by beams of the small particles called by electrons. The choice of a type of radiation therapy depends on a look and a stage of an oncological disease.
Chemotherapy – a way of treatment of oncological diseases by means of strong chemotherapeutic drugs. Chemotherapeutic drugs are capable to stop growth of cancer cells and to destroy them, to prevent their department and penetration into other fabrics and bodies. Chemotherapeutic drugs can orally be accepted (in the form of tablets, capsules) or are entered injektsionno intravenously or intramusculary. Medicinal substance gets to a blood stream, together with blood spreads on an organism and strikes cancer cells (systematic chemotherapy). If the chemotherapeutic drugs are administered directly in a rachis (intrathecal chemotherapy), body or a perigastrium (chest, belly), medicinal substance strikes mainly cancer cells in these sites (regional chemotherapy). Treatment is in certain cases carried out by topical chemotherapy (leather is processed by cream or lotion). The choice of a type of chemotherapy depends on a look and a stage of an oncological disease.
Other medicamentous therapies. Treatment by retinoids which are medicinal substances vitamin A derivatives. Retinoids can slow down growth of cancer cells of a certain look. Retinoids can be accepted orally or outwardly (on skin).
Biological therapy.
Biological therapy is a way of treatment which involves immune system of the patient for fight against an oncological disease. Substances which are produced in an organism or which are synthesized in laboratory are used for recovery or stimulation of natural mechanisms of protection for fight against an oncological disease. This type of treatment of oncological diseases is also called a biotherapy or an immunotherapy.
