9 months of Potassium iodide

General characteristics. Structure:

Active agent: potassium iodide of 262 mkg, including iodine of 200 mkg.

Pharmacological properties:

At intake of iodides in cells of an epithelium of a follicle of a thyroid gland iodine ions under the influence of enzyme iodide-peroxidase are oxidized with formation of elementary iodine which joins in a tyrosine molecule. At the same time one part of radicals of tyrosine in thyreoglobulin is iodated therefore it is formed tironina, thyroxine (T4) and triiodothyronine (Тз) are basic of which. The formed complex of tironin and thyreoglobulin is allocated as the deposited form of hormone of a thyroid gland in a colloid of a follicle and remains in such state within several days or weeks. At an iodine deficiency this process is broken.
Potassium iodide, compensating an iodine deficiency, promotes recovery of the broken synthesis of thyroid hormones, normalizes T3/T4 ratio indicators, thereby normalizes function of a thyroid gland and eliminates symptoms of iodic deficit.

Pharmacokinetics. Absorption - bystry and full. Concentration in plasma - 0.1 - 0.5 mkg/dl. It is intensively absorbed by a thyroid gland where is oxidized to iodine. Substratno provides iodination of tyrosine in a thyroid gland with education mono - and diiodotyrosine, TZ and T4. Collects also in the salivary and lactating mammary glands, stomach tissue (content in saliva, milk and a gastric juice exceeds plasma level by 30 times).

It is removed by kidneys, partially - bronchial, salivary and lacrimal glands.

Indications to use:

— prevention of emergence of an iodine deficiency in the woman's organism at pregnancy and during breastfeeding when intake of iodine with food makes less than 150-300 mkg/days.

Route of administration and doses:

Inside, during food, washing down with enough liquid. To apply after consultation with the doctor.

Prevention of emergence of an iodine deficiency in the woman's organism at pregnancy and in the period of a chest vskarmpivaniye: 9 months of Potassium iodide appoint in a dose 200 mkg / суг (1 tablets), at the same time the concomitant use of other yodsolerzhashchy drugs is not recommended. Duration of a course is determined by the doctor.

Features of use:

Long reception of potassium of iodide in the doses exceeding 1000 mkg/days causes decrease in digestion of iodine a thyroid gland and synthesis of thyroid hormones that is shown further in the form of a hypothyroidism and developing of a craw.
Against the background of therapy at patients with a renal failure development of a hyperpotassemia is possible.

Side effects:

At use of 9 months of Potassium of iodide according to indications in the recommended doses emergence of side effects is improbable.

Allergic reactions: skin rash, Quincke's edema.

Interaction with other medicines:

Anti-thyroid medicines and potassium iodide mutually weaken effects of each other.
Potassium perchlorate and potassium thiocyanate suppress iodine absorption by a thyroid gland.
Thyritropic hormone improves digestion of iodine a thyroid gland and stimulates production of its hormones.
The concomitant use of inhibitors of an angiotensin-converting enzyme (including captopril, enalapril, lisinopril) increases risk of emergence of a hyperpotassemia.
High doses of iodine in combination with kaliysberegayushchy diuretics can lead to a hyperpotassemia.
Therapy co-administration by iodine in high doses and drugs of lithium promotes development of a craw and a hypothyroidism.

Contraindications:

— the expressed and hidden hypothyroidism;
— herpetiform dermatitis;
— hypersensitivity to iodine.
Iodide it is not necessary to accept potassium at a hypothyroidism unless development of the last is caused by the expressed iodine deficiency. Purpose of drug should be avoided at therapy by a radioiodine, existence or at suspicion of cancer of a thyroid gland.

Use at pregnancy and feeding by a breast
During the periods of pregnancy and a lactation the need for iodine increases. 9 months of Potassium appoint iodide according to indications when intake of iodine with food makes less than 150-300 mkg /
Drug well gets through a placenta and at reception in a dose over 500 mkg / ки can cause development of a hypothyroidism and a craw in a fruit. Iodine is also emitted with breast milk. At use for mother in the period of a lactation in doses more than 1000 mkg / сугки arise risk of development of a hypothyroidism in the baby.
Therefore at pregnancy and in the period of a lactation drug should be used only in the recommended doses.

Use at renal failures
Against the background of therapy at patients with a renal failure development of a hyperpotassemia is possible.

Overdose:

Symptoms: coloring of mucous membranes in brown color, vomiting, abdominal pains and diarrhea (the melena is possible). In hard cases development of dehydration and shock is possible.

Treatment: gastric lavage, introduction of Natrium thiosulfuricum, symptomatic therapy of disturbance of water and electrolytic balance, antishock therapy.
The chronic overdose can lead to development of a phenomenon of an iodism: "metal" smack in a mouth; hypostasis and inflammation of mucous membranes (rhinitis, conjunctivitis, gastroenteritis, bronchitis); acne rash; dermatitis; hypostasis of sialadens; fever; nervous irritability.
Treatment at chronic overdose: drug withdrawal.

Storage conditions:

To store drug in the dry place protected from light at a temperature not above 25 °C. To store in the place, unavailable to children.

Issue conditions:

Without recipe

Packaging:

Tablets of 200 mkg: 50.