DE   EN   ES   FR   IT   PT


medicalmeds.eu Medicines Antimicrobic and antiprotozoan means. Ornidazol-vero

Ornidazol-vero

Препарат Орнидазол-веро. ОАО "ВЕРОФАРМ" Россия


Producer: JSC VEROPHARM Russia

Code of automatic telephone exchange: J01XD03

Release form: Firm dosage forms. Tablets.

Indications to use: Trichomoniasis. Amebiasis. Abenteric amebiasis. Amoebic abscess of a liver. Lambliasis.


General characteristics. Structure:

Active agent: орнидазол 500 mg. Excipients: starch corn, cellulose microcrystallic, polyvinylpirrolidone (povidone), sodium carboxymethylstarch (примогель), magnesium stearate cover: oksipropilmetiltsellyuloza, polyvinylpirrolidone (povidone), twin-80 (polysorbate), talc, titanium dioxide.




Pharmacological properties:

Pharmacodynamics. Ornidazol is active concerning trichomonads, lyambliya, a dysenteric amoeba, some anaerobic microorganisms (Bacteroides spp., Fusobacter spp., Clostridium spp., and anaerobic cocci).

Pharmacokinetics. Absorption from digestive tract — high. Bioavailability — 90%. Time of achievement of the maximum concentration (Tcmax) — 1–2 h. Communication with proteins of plasma — not less than 15%. Gets through a blood-brain barrier. An elimination half-life (T1/2) — about 13 h. It is removed in the form of metabolites by kidneys (60–65%) and with a fecal masses (20–22%), about 5% of a dose are removed in not changed look.


Indications to use:

Trichomoniasis, amebiasis, amoebic dysentery, abenteric amebiasis (in t.   h amoebic abscess of a liver); lambliasis; prevention of the postoperative infectious complications caused by anaerobic bacteria at surgical intervention on a large intestine and gynecologic operations.


Route of administration and doses:

Inside, after food. At trichomoniasis: adult — 0,5 g 2 times a day within 5 days. To children — in a single dose, at the rate of 25 mg/kg of body weight a day. At amoebic dysentery to adults and children with body weight over 35 kg — 1,5 g 1 times/days, at body weight over 60 kg — 2 g/days. To children with body weight less than 35 kg — 40 mg/kg/days. Treatment duration — 3 days. For treatment of other forms of an amebiasis: to adults and  children weighing more than 35 kg — on 0,5 g in 2 times a day,  weighing up to 35 kg — 25 mg/kg once within 5–10 days. At a lambliasis: to adults and children with body weight over 35 kg — inside, on 1,5 g of 1 times a day; to children with body weight to 35 kg — on 40 mg/kg/days. Treatment duration — 1–2 days. Prevention of the postoperative infectious complications caused by anaerobic bacteria — 0,5 g before operation, then each 12 hours on 0,5 g, within 3–5 days.


Features of use:

At treatment of trichomoniasis it is necessary to carry out simultaneous treatment of both partners.


Side effects:

Headache, dizziness, consciousness disturbance, tremor, rigidity, diskoordination of movements, spasms, the touch or mixed peripheral neuropathy, dispepsichesky frustration.


Interaction with other medicines:

Strengthens effect of anticoagulants of a coumarinic row, prolongs myorelaxation action a bromide vekuroniya. In difference from other imidazolovy derivatives (metronidazole), we will combine with alcohol (does not inhibit an atsetaldegiddegidrogenaza).


Contraindications:

Hypersensitivity, pregnancy (I trimester), lactation period, organic diseases of the central nervous system.


Overdose:

Symptoms: epileptiform spasms, depression, peripheral neuritis. Treatment: symptomatic.


Storage conditions:

 List B. In dry, protected from light and the place, unavailable to children, at a temperature not above 25 °C. A period of validity - 2 years. Not to use drug after the date specified on packaging.


Issue conditions:

According to the recipe


Packaging:

Tablets, coated 0,5 g. On 10 tablets in a blister strip packaging. On 10 tablets in bank of orange glass. Each can or 1 blister strip packaging together with the instruction in a pack from a cardboard.



Similar drugs

Препарат Тиберал. ОАО "ВЕРОФАРМ" Россия

Tiberal

Antimicrobic and anti-protozoan means.





  • Сайт детского здоровья