Abenteric amebiasis

Description:

The abenteric amebiasis is characterized by damage of various internals and development of amoebic pneumonia, abscesses of a brain and liver, a skin amebiasis.

Symptoms of the Abenteric amebiasis:

Amoebic pneumonia proceeds with inflammatory changes in lungs and develops as a result of an activator drift from the centers of defeat in a large intestine or liver with blood in lungs; has a long current and in the absence of specific treatment formation of abscess of a lung is possible. The amoebic encephalomeningitis (amoebic abscess of a brain) proceeds with displays of the expressed intoxication, focal neurologic frustration; formation of multiple abscesses preferential in the left cerebral hemisphere is characteristic. The skin amebiasis is characterized by formation of low-erethistic ulcers with the subdug uneven edges and an unpleasant smell, ulcers form on skin of a crotch, generative organs, in the field of fistulas and postoperative wounds.

Reasons of the Abenteric amebiasis:

The amebiasis activator — a dysenteric amoeba — F. A. Lesh in 1875 in St. Petersburg in Calais for the first time found the patient, it is long having a bloody diarrhea. In 1883 Koch in Egypt at a pathoanatomical research of corpses of the people who died of dysentery found amoebas in microscopic sections of fabrics of intestinal ulcers and walls of abscess of a liver.

In 1903 F. Shaudinn submitted the detailed description of a dysenteric amoeba. In 1912 muriatic emetine was entered into practice of treatment of an amebiasis.

Disease-producing factor is Entamoeba histolytica.

Distinguish two forms of dysenteric amoebas — vegetative and intsistirovanny which can pass one into another depending on dwelling conditions in the owner's organism.

Treatment of the Abenteric amebiasis:

For treatment of patients with abenteric complications the following scheme is used. Metronidazole on 750 mg 3 times a day within 5 – 10 days in combination with yatren (Chiniofonum) on 650 mg three times a day during 20 days is appointed or instead of yatren appoint chloroquine phosphate (Chingaminum, delagil) in a dose the first two days on 1 g a day, then on 0,5 g a day during 4 weeks Besides, appoint дегидроэметнн intramusculary 1 mg/kg a day during 10 days. In certain cases to the specified drugs furasolidone (on 0,1 g 4 times a day during 10 days) which, though does not give effect without other drugs in addition is appointed, but in a complex with them improves results of therapy. At the abscesses of a liver which are not giving in to conservative treatment (as a rule, exceed 2 cm in the diameter), the transdermal puncture under control of ultrasonography with the subsequent its drainage and washing of a cavity with use of amebotsidny means (delagil, emetine) is shown. Effectively transumbilikalny administration of amebotsidny drugs (emetine, delagil).