Алька-Прим®

General characteristics. Structure:

Active agents: 330 mg of acetylsalicylic acid, 100 mg of the aminoacetic acid (glycine).

Excipients: citric acid anhydrous, Natrii hydrocarbonas.

Pharmacological properties:

Pharmacodynamics. Analgetic, antiinflammatory, an antipyretic, nootropic, the means normalizing a metabolism, antioxidant, anti-toxic.

Drug begins to work already 30 minutes later from the moment of reception, and the maximum action is shown 1-4 hours later and keeps within 3-6 hours after use of a single dose.

Pharmacokinetics. After intake drug is quickly soaked up from a digestive tract. At patients with normal function of kidneys of 80-100% of a single dose it is removed with urine within 24-72 hours.

Indications to use:

Headache at a hungover syndrome (an alcoholic abstinence syndrome), a moderate pain syndrome: head, muscular, tooth, menstrual pains, dorsodynias.

The increased body temperature at catarrhal and other virus infectious diseases (at adults and children 15 years are more senior).

Route of administration and doses:

Sparkling tablets should be dissolved in a glass of water and to drink. Usually on 1-2 tablets 2-4 times a day with an interval not less than 4 hours. The maximum single dose — 1 g (3 tablets). The maximum daily dose for adults which it is not recommended to exceed — 3 g (9 tablets).

It is not necessary to use drug more than 7 days as an anesthetic and more than 3 days, as an antipyretic without medical observation.

Features of use:

It is recommended to use drug under medical control to the persons having allergic diseases (bronchial asthma, allergic rhinitis, a small tortoiseshell, a skin itch, a rhinedema).

At use of acetylsalicylic acid by the patient receiving anti-diabetic means it is necessary to control blood sugar level regularly.

Careful observation is demanded by the combined use of drug with glucocorticoids, anti-hypertensive and diuretics; the antiacid drugs containing a hydroxide of magnesium or aluminum should be accepted not earlier than in 2 (two) hours after reception of acetylsalicylic acid.

At prolonged use of drug it is necessary to do periodically the general blood test and to check availability of blood in Calais.

Lactation period. Breastfeeding is not recommended during long therapy by high doses of acetylsalicylic acid though short-term use of single doses of drug does not pose a big threat for feeding of the baby.

Side effects:

After use of acetylsalicylic acid were observed: nausea, vomiting, lack of appetite, an abdominal pain, bleeding, a sonitus, rash on skin, bleeding of mucous membranes, changes in composition of blood.

Hypersensitivity reaction: small tortoiseshell, Quincke's disease (Quincke's edema), spasm of bronchial tubes, shock, dacryagogue, collapse, loss of consciousness. Patients with bronchial asthma, polyps of a nose or a chronic small tortoiseshell make group of the increased risk.

Some patients have side effects, both urticaria, and shock, can develop within 3 hours after administration of drug.

Interaction with other medicines:

Strengthens effect of peroral anticoagulants and hypoglycemic medicines, insulin, a methotrexate, other non-steroidal anti-inflammatory drugs, glucocorticosteroids, valproic acid, ethanol.

Weakens effect of Sulfinpyrazonum, diflunizal, the phenopro-hair dryer, an ibuprofen, indometacin, piroxicam, Naproxenum, sulindak, and also the medicines blocking canalicular secretion.

Myelotoxic medicines strengthen manifestations of a gematotoksichnost of drug.

Contraindications:

^{Алька-Прим®} it is not necessary to apply at the following states:

• the known hypersensitivity to acetylsalicylic acid or other salicylates;
• the bronchospasm caused by salicylates;
• hemorrhagic diathesis;
• peptic ulcer of a stomach or 12-perstny gut;
• the expressed abnormal liver functions and kidneys;
• blood coagulation disturbances (hemophilia, thrombocytopenia);
• deficit dehydrogenase glyukozo-6-phosphate;
• during pregnancy, especially it is not recommended to use drug during the last three months of pregnancy (III) trimester, in view of possible malformations of a fruit and complications at the time of delivery;
• lactation period.

Drug is not appointed to children up to 15 years with the acute respiratory diseases caused by viral infections (danger of development of a syndrome to Reja).

With care — at elderly people.

Overdose:

Heavy symptoms of intoxication at reception over 200 mg/kg. At suspicion of poisoning it is necessary to ask for medical care immediately. In an initial stage of poisoning symptoms of excitement of the central nervous system, dizziness, a vision disorder and hearing, nausea, vomiting, breath strengthening develop. There comes oppression of consciousness up to a coma, respiratory insufficiency, disturbances of water and electrolytic exchange later. At symptoms of poisoning it is necessary to cause vomiting or to make a gastric lavage, to appoint absorbent carbon.

Treatment should be carried out in the conditions of specialized department.

Storage conditions:

To store in dry, protected from light and the place, unavailable to children, at a temperature not over 25 to the °sena to use after the date specified on packaging. A period of validity - 2 years.

Issue conditions:

Without recipe

Packaging:

Tablets are sparkling. On 2 or 10 tablets in strips from aluminum foil. 1 or 5 strips with 2 tablets or 1 strip with 10 tablets in a cardboard pack with the application instruction.