Aminalonum

General characteristics. Structure:

Active ingredient: 250 mg gamma аминобутировой acids.

Excipients: sucrose (the granulated sugar refined); stearate magnesium monohydrate.

Cover: magnesium hydroxycarbonate (magnesium carbonate the main); wheat flour.

Psychogogic action possesses: improves cerebration, memory, concentration of attention, and also poslablyat vestibular disturbances, a sleep disorder. Drug promotes resuming of movements, the speech, other cortical functions after disturbance of cerebral circulation.

Pharmacological properties:

Pharmacodynamics. Gamma аминобутировая acid (GABA, piperidic acid) is biogenic amine, recovers processes of metabolism in a brain, promotes glucose utilization by a brain and to removal from it toxic products of exchange, provides normalization of dynamics of nervous processes in a brain. Increases productivity of thinking, improves memory, has soft psychogogic effect, favorably influences recovery of movements and the speech after disturbance of cerebral circulation. Promotes decrease and stabilization of the raised ABP and reduction of subjective symptoms of arterial hypertension (dizziness, a sleep disorder).

Has moderate anti-hypoxemic and anticonvulsant effect. At patients with a diabetes mellitus reduces the content of glucose, at the normal content of glucose in blood renders converse effect (at the expense of a glycogenolysis).

Pharmacokinetics. Absorption is bystry, rather full. Cmax in a blood plasma is reached in 60 min., then concentration quickly decreases. By 24 h GABA is not defined in a blood plasma.

Indications to use:

States after the postponed disturbances of cerebral circulation; after craniocereberal injuries. Atherosclerosis of brain vessels with the brain softening phenomena. Alcoholic encephalopathy and polyneurites. A headache, dizziness, sleep disorders at arterial hypertension. Cerebral palsy; effects of a craniocereberal and birth trauma at children; lag of intellectual development in children; kinetoza.

Route of administration and doses:

The daily dose for adults makes - 3-3.75 g. To children aged from 1 year up to 3 years - 1-2 g/days; from 4 to 6 years - 2-3 g/days; 7 years - 3 g/days are more senior. The daily dose for children and adults is divided into 3 receptions and accepted to food. The course of treatment proceeds from 2-3 weeks to 2-4 months.

For prevention and treatment of kinetoz by the adult - on 500 mg of 3 times/days during 3-4 days, to children - on 250 mg of 3 times/days during 3-4 days.

Features of use:

In the first days of treatment fluctuations of the ABP are possible.

Use for children is possible according to the dosing mode.

Side effects:

Are possible: nausea, vomiting, lability of the ABP, dyspepsia, fervescence, sleep disorder.

Interaction with other medicines:

At simultaneous use strengthening of action of derivatives of benzodiazepine, many hypnotic drugs and antiepileptic means is possible.

Contraindications:

Hypersensitivity to GABA.

Overdose:

At considerable exceeding of therapeutic doses of drug, non-compliance with the recommended schemes of treatment nausea, vomiting, disturbances intestines, a headache, temperature increase, fluctuations of arterial pressure, a sleep disorder can develop. It is necessary to stop administration of drug. Symptomatic treatment.

Storage conditions:

List B. In the dry, protected from light place and the place, unavailable to children, at a temperature not above 25 degrees Celsius.

Issue conditions:

According to the recipe

Packaging:

100 pieces - banks polymeric (1) - packs cardboard.
100 pieces - banks of dark glass (1) - a pack cardboard.
100 pieces - banks (1) - packs cardboard.