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medicalmeds.eu Medicines Polyfermental drugs (lipase + protease, etc.). TB Pancreatinum. п / about 30 PIECES No. 60

TB Pancreatinum. п / about 30 PIECES No. 60

Препарат Панкреатин тб. п/о 30 ЕД №60. ЗАО "Фармпроект" Россия


Producer: CJSC Pharmproyekt Russia

Code of automatic telephone exchange: A09AA02

Release form: Firm dosage forms. Tablets.

Indications to use:


General characteristics. Structure:

Active ingredient: Pancreatinum of 30 PIECES.




Pharmacological properties:

Fermental means. Contains pancreatic enzymes - amylase, a lipase and proteases which facilitate digestion of carbohydrates, fats and proteins that promotes their fuller absorption in a small bowel. At diseases of a pancreas compensates insufficiency of its vneshnesekretorny function and promotes digestion process improvement.

Pharmacokinetics. The pharmacokinetics of Pancreatinum is not studied.


Indications to use:

Insufficiency of vneshnesekretorny function of a pancreas (including at chronic pancreatitis, a mucoviscidosis). Chronic inflammatory and dystrophic diseases of a stomach, intestines, liver, gall bladder; the states after a resection or radiation of these bodies which are followed by disturbances of digestion of food, a meteorism, diarrhea (as a part of a combination therapy). For improvement of digestion of food at patients with the GIT normal function in case of errors in food, and also at disturbances of chewing function, a forced long immobilization, a slow-moving way of life. Preparation to radiological and to ultrasound examination of abdominal organs.


Route of administration and doses:

The dose (in terms of a lipase) depends on age and degree of insufficiency of function of a pancreas. An average dose for adults - 150 PIECES/days. At full insufficiency of vneshnesekretorny function of a pancreas - 400 PIECES/days that corresponds to daily need of the adult for a lipase. Maximum dose: 15 - 20 PIECES/kg/days. To children aged up to 1.5 years - 50 PIECES / cут; 1.5 years - 100 PIECES/days are more senior. Duration of treatment can vary of several days (at disturbance of process of digestion owing to errors in a diet) up to several months and even years (in need of continuous replacement therapy).


Features of use:

Use in a phase of an exacerbation of chronic pancreatitis is not recommended. At a mucoviscidosis the dose has to be adequate to amount of enzymes which is necessary for absorption of fats taking into account quality and amount of the consumed food. At a mucoviscidosis use of Pancreatinum in doses more than 10 000 PIECES/kg/days (in terms of a lipase) owing to increase in risk of development of strictures (a fibrous colonopathy) in ileocecal department and in the ascending colon is not recommended. At high activity of the lipase which is contained in Pancreatinum the probability of development of locks in children increases. Increase in a dose of Pancreatinum at this category of patients should be carried out gradually. Disturbances from the alimentary system can arise at patients with hypersensitivity to Pancreatinum, or at patients with mekoniyevy Ilheus or a resection of intestines in the anamnesis. Safety of use of Pancreatinum at pregnancy is studied insufficiently. Use is possible in cases when the expected advantage for mother exceeds potential risk for a fruit. In pilot studies it is established that Pancreatinum has no teratogenic effect.


Side effects:

At use in average therapeutic doses side effect is observed less, than in 1%. From the alimentary system: in some cases - diarrhea, a lock, a sensation of discomfort in a stomach, nausea. Relationship of cause and effect of development of these reactions is not established with action of Pancreatinum since the specified phenomena belong to symptoms of vneshnesekretorny insufficiency of a pancreas. Allergic reactions: in some cases - skin manifestations. From a metabolism: at prolonged use in high doses development of a hyper uricosuria, in excessively high doses - increase in level of uric acid in a blood plasma is possible. Other: at use of Pancreatinum in high doses at children emergence of perianal irritation is possible.


Interaction with other medicines:

At simultaneous use with the antacids containing calcium a carbonate and/or magnesium hydroxide reduction of efficiency of Pancreatinum is possible. At simultaneous use reduction of clinical performance of acarbose is theoretically possible. At simultaneous use of iron preparations iron absorption reduction is possible.


Contraindications:

Acute pancreatitis. Hypersensitivity to Pancreatinum.




Issue conditions:

According to the recipe


Packaging:

In packaging on 60 tablets.



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