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Pancreatinum

Препарат Панкреатин. ОАО "Ирбитский химико-фармацевтический завод" Россия


Producer: JSC Irbit Chemical and Pharmaceutical Plant Russia

Code of automatic telephone exchange: A09AA02

Release form: Firm dosage forms. Tablets.

Indications to use: Chronic pancreatitis. Akhillodiniya. Anacid gastritis. Gipoatsidny gastritis. Chronic coloenteritis.


General characteristics. Structure:

Active agents: Pancreatinum 0,1g (proteolytic activity not less-25 than A PIECE, lipolytic activity not less – 140 PIECES, amylolytic activity not less – 1500 PIECES).

Excipients: lactose (sugar milk), MTs-16 methyl cellulose, calcium stearate, целацефат, acid red 2C, titanium dioxide, polisorbat-80.

Description. Tablets, coated, pink or dark pink color, round, biconvex, with a specific smell. On cross section of a kernel of a tablet existence of impregnations is allowed.




Pharmacological properties:

Completion of deficit of enzymes of a pancreas. Contains excretory pancreatic enzymes: a lipase, alpha amylase, trypsin, chymotrypsin, promotes the proteolysis (to amino acids), fats (to glycerin and fatty acids) and starch (to dextrins and monosaccharides), normalizes digestion processes. The enzymes which are a part of Pancreatinum are released in the alkaline environment of a small intestine since are protected from action of a gastric juice by a cover. Trypsin in the upper site of a small intestine inhibits stimulated secretion of a pancreas, causing analgesic effect of Pancreatinum.


Indications to use:

Apply at an akhiliya, chronic pancreatitis with insufficient function of a pancreas, at the digestive disturbances connected with diseases of a liver and pancreas, anacid and subacid gastritis, chronic coloenterites.


Route of administration and doses:

Pill is taken during food or at once after it, without getting to the core. For adults the single dose of Pancreatinum makes 0,5-1,0 g, daily - 4 g.

Drug in tablets is appointed to children in the following doses: at the age of 6-7 years 1 tablet, 8-9 years 1-2 tablets, 10-14 years 2 tablets.

The course of treatment makes from 4-6 weeks to 2-3 months and more. 


Features of use:

It is not described.


Side effects:

Symptoms of intestinal impassability (formation of strictures in ileocecal department and the ascending obolochny gut) and allergic reactions of immediate type  (at a mucoviscidosis, especially at children).


Interaction with other medicines:

Reduces iron absorption (especially at prolonged use).


Contraindications:

Hypersensitivity (including intolerance of pork), acute pancreatitis, exacerbation of chronic pancreatitis.


Overdose:

Cases are not described.


Storage conditions:

Period of validity 2 years. After a period of validity not to use drug. In the dry  place, at a temperature from 12 to 20 °C.


Issue conditions:

Without recipe


Packaging:

The tablets covered with a kishechnorastvorimy cover of 25 PIECES.

On 10 tablets in a blister strip packaging from a film of polyvinyl chloride and aluminum foil. On 60 tablets in bank of orange glass, corked by the tense plastic cover or  in bank from polymeric materials with the screwed cover. The free space in bank is filled with medical cotton or a sealant from polyethylene. On bank paste the label from paper label or writing, or self-adhesive.

6 blister strip packagings or to bank with the application instruction place in a pack from a cardboard bandbox.



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