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Acute tubular necrosis


Acute tubular necrosis of kidneys – frustration with participation of the damaged cells of tubules of kidneys that leads to an acute renal failure. The necrosis is caused by a lack of oxygen of tissues of kidneys (ischemia of kidneys). OTN is one of the most widespread structural changes which can lead to an acute renal failure. OTN is one of the most common causes of a renal failure at the hospitalized patients.

Symptoms of the Acute tubular necrosis:

    * Decrease in consciousness (coma, nonsense or confusion, drowsiness, slackness)
    * Decrease in a diuresis
    * Hypostases
    * Nausea, vomiting

Note: other symptoms of an acute renal failure, can be also present.

Reasons of the Acute tubular necrosis:

Risks for an acute necrosis include:

    * Reaction of hemotransfusion
    * Injury
    * Serious operations
    * Septic shock or other forms of shock
    * Heavy low blood pressure (hypotonia)

The diseases of a liver and kidneys caused by diabetes can make the person more susceptible to a condition.

OTN can be caused:

    * Influence of drugs which are toxic for kidneys
    * Antifungal drugs
    * X-ray

Treatment of the Acute tubular necrosis:

At most of people the acute tubular necrosis is reversible. The purpose of treatment consists in the prevention of life-threatening complications from an acute renal failure. Treatment is focused on prevention of excess accumulation of liquid and waste, allowing at the same time kidneys to heal. Treatment can include:

    * Identification and treatment of the main reason for a problem
    * Restriction of consumption of liquid in the volume equal to urine volume
    * Restriction of substances which are usually removed from an organism by kidneys (for example, protein, sodium, potassium) to minimize their accumulation in an organism
    * Prinimany drugs to control potassium level in blood

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