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medicalmeds.eu Medicines Histamine drug. Beta beliefs

Beta beliefs

Препарат Бетавер. ОАО "ВЕРОФАРМ" Россия


Producer: JSC VEROPHARM Russia

Code of automatic telephone exchange: N07CA01

Release form: Firm dosage forms. Tablets.

Indications to use: Dizziness. Sonitus. Decrease in hearing. Menyer's disease. Headache.


General characteristics. Structure:

Active ingredient: a betagistina dihydrochloride - 24 mg;
excipients: cellulose microcrystallic, lactose (sugar milk), starch corn, POVIDONE (polyvinylpirrolidone), sodium carboxymethylstarch (примогель), talc, silicon dioxide colloid (aerosil).




Pharmacological properties:

Betagistin affects mainly histamine N1-and H3 receptors of an inner ear and vestibular nuclei of the central nervous system. By direct agonistic impact on H1 receptors of vessels of an inner ear, and also indirectly through impact on H3 receptors improves microcirculation and permeability of capillaries of an inner ear, normalizes endolymph pressure in a labyrinth and a snail. At the same time бетагистин increases a blood stream in a basilar artery.

Has the expressed central effect, being H3 receptors inhibitor of kernels of a vestibular nerve. Normalizes conductivity in neurons of vestibular nuclei at the level of a brain trunk.

Clinical manifestation of the specified properties is decrease in frequency and intensity of dizzinesses, reduction of a sonitus, improvement of hearing in case of its decrease.


Pharmacokinetics. Communication with proteins of plasma — low is absorbed quickly. The maximum concentration in a blood plasma in 3 hours. An elimination half-life in 3–4 hours. It is almost completely removed by kidneys in the form of a metabolite (2-peridiluksusny acid) within 24 hours.


Indications to use:

Treatment and prevention of vestibular dizziness of various origin. The syndromes including dizziness and a headache, a sonitus, the progressing decrease in hearing, nausea and vomiting. Menyer's disease/syndrome.


Route of administration and doses:

Inside, during food.

Beta beliefs of 8 mg — 1–2 tablets 3 times a day.
Beta beliefs of 16 mg-½-1 a tablet 3 times a day.

Improvement is usually noted already at the beginning of therapy, the stable therapeutic effect comes after two weeks of treatment and can increase within several months of treatment. Duration of administration of drug is selected individually.
Side effect

Gastrointestinal frustration. It was seldom or never reported about emergence of hypersensitivity reactions from integuments (rash, an itch, urticaria); Quincke's edema.



Side effects:

Gastrointestinal frustration. It was seldom or never reported about emergence of hypersensitivity reactions from integuments (rash, an itch, urticaria); Quincke's edema.


Interaction with other medicines:

Cases of interaction or incompatibility with other medicines are unknown.
Influence on ability to driving and other mechanisms

Beta beliefs do not possess sedation and does not influence ability to drive the car or to work at machines and mechanisms.


Contraindications:

Hypersensitivity to any of drug components, pregnancy and a lactation (in connection with insufficiency of data). With care: a peptic ulcer of a stomach of a 12-perstny gut (in t.   h in the anamnesis), a pheochromocytoma, bronchial asthma. The specified patients should be observed regularly during treatment.


Overdose:

Symptoms: nausea, vomiting, emergence of spasms at reception of a dose over 640 mg is possible.
Treatment: gastric lavage, reception of absorbent carbon, symptomatic therapy.


Storage conditions:

List B. In the dry, protected from light place at a temperature not above 25 °C. To store in the place, unavailable to children. A period of validity - 2 years. Not to use after the period of validity specified on packaging.


Issue conditions:

According to the recipe


Packaging:

Mg tablets 8 and 16. On 10 tablets in a blister strip packaging. On 3 blister strip packagings together with the application instruction in a pack from a cardboard.
On 30 tablets in bank of orange glass. Each can together with the application instruction in a pack from a cardboard.



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