Tumors of epithelial bodies

Description:

Benign tumors of epithelial bodies (adenoma) and zlokayochestvenny tumors (cancer) meet seldom and practically always have hormonal activity that is an important diagnostic priyoznak.

Symptoms of Tumours of epithelial bodies:

Adenomas develop from the main parathyreocytes more often and are localized in one of the lower glands. At increase in sizes of several parashchitovidnykh glands it is necessary to carry out the differential diagnosis with a hyperplasia. In a clinical picture into the forefront the hyperparathyreosis phenomena act. In topical diagnosis the great value is attached ultrasonography with a tonkoyoigolny biopsy, to the combined radio isotope research, KT and MPT. In difficult diagnostic cases carry out seyolektivny arteriography and the selection intake of blue blood for a parathormone level issleyodovaniye. Treatment surgical - removal of adenoma.

Cancer. Malignant transformation of epithelial bodies is revealed at primary hyperparathyreosis in 0,5-4,6% of observations. The disease meets identical frequency at men and women usually at the age of 50-60 years. The family form of cancer, and also cancer parathyroid же­лез is described at MEN-1 syndrome.

Symptoms of tumors of epithelial bodies  are typical for primary hyperparathyreosis, the expressed hypercalcemia is veduyoshchy. Hormonal and inactive forms are diagnosed extremely seldom (less than 5%). The carcinoma sizes usually it is more, than the adenoma sizes. The palpated educations on a neck are defined only in 5% of observations. Almost at 30% of patients metastasises in regional lymph nodes of a neck come to light, quite often they are closely soldered to a thyroid gland, a trachea, a gullet that complicates udaleyony tumors. Sometimes paresis of a recurrent guttural nerve develops. Otyodalenny innidiation happens preferential in lungs, is more rare - in a liver and bones.

Reasons of Tumours of epithelial bodies:

The etiology of a disease is unknown. There is an opinion that a provocative role in development of cancer of thyroid gland is played by increase in products of thyritropic hormone and stimulation of hyperplastic processes by it. The ionizing radiation, in particular the previous radiation therapy can play a part. Cancer of a thyroid gland develops against the background of nodal, including local, a craw and makes about 90 - 95% of all malignant tumors of this body.

Treatment of Tumours of epithelial bodies:

Treatment of tumors of epithelial bodies surgical - an oncotomy with an adjacent share of shchitoyovidny gland. At increase in regional lymph nodes vypolyonyat a limfadenektomiya. During operation it is necessary to avoid a rupture of a kapyosula of a tumor for the purpose of prevention of an implantation recurrence. The Mestyony recurrence is observed often - to 50%.