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Xyflax

Препарат Ксилен. ОАО "ВЕРОФАРМ" Россия


Producer: JSC VEROPHARM Russia

Code of automatic telephone exchange: R01AA07

Release form: Liquid dosage forms. Drops are nasal.

Indications to use: Rhinitis (cold). Allergic rhinitis (cold). Sinusitis. Average otitis. Rinoskopiya.


General characteristics. Structure:

Active ingredients: 100 ml of solution for topical administration contain xylomethazolinum of a hydrochloride 0,1 and 0,05 g; in bottles on 10 ml or in bottles on 10 ml with a cover dropper, in a box 1 bottle.




Pharmacological properties:

Xylomethazolinum concerns to group of local vasoconstrictors (decongestants) with an alpha adrenomimeticheskoy activity, causes narrowing of blood vessels of a mucous membrane of a nose, eliminating, thus, hypostasis and a hyperemia of a mucous membrane of a nose, recovers passability of the nasal courses, facilitates nasal breath. Effect of drug comes in a few minutes after its use and continues  till 10 o'clock.

Pharmacokinetics. At topical administration drug is practically not soaked up therefore its concentration in a blood plasma is very small (by modern analytical methods is not defined).


Indications to use:

Apply at acute respiratory diseases with the phenomena of rhinitis (cold), acute allergic rhinitis, sinusitis, at average otitis ( as a part of a combination therapy to reduction of hypostasis of a mucous nasopharynx), to simplification of carrying out a rinoskopiya.


Route of administration and doses:

To adults and children 6 years are more senior enter on 1 — 2 drops 0,1% of solution of xylomethazolinum into each nasal course 2 — 3 times a day.    Apply 0,05% to babies and children under 6 years solution on 1 — 2 drops in each nasal course of 1 — 2 time a day. It is not necessary to use drug more often than 3 times a day and no more than 3 — 5 days. Not to use drug without interruption more than 3 — 5 days.


Features of use:

Before use it is necessary to clear the nasal courses. It is not necessary to apply for a long time, for example, at chronic rhinitis. The passed dose: within 1 hour to use at once, after 1 h not to use; not to double a dose. Influence on ability to manage the vehicle or the equipment: Xylomethazolinum, in the dosages exceeding recommended can influence ability to manage the vehicle and to be engaged in other potentially dangerous types of activity demanding concentration of attention and speed of psychomotor reactions.


Side effects:

At frequent and/or prolonged use — irritation and/or dryness of a mucous membrane of a nasopharynx, burning, parasthesias, sneezing, hypersecretion; seldom — a rhinedema, vomiting, a headache, heartbeat, increase in arterial pressure, tachycardia, arrhythmia, sleeplessness, a vision disorder, a depression (at prolonged use of high doses).


Interaction with other medicines:

It is incompatible with monoamine oxidase inhibitors (MAO) and tricyclic antidepressants.


Contraindications:

Hypersensitivity to xylomethazolinum and other components of drug, arterial hypertension, tachycardia, the expressed atherosclerosis, glaucoma, atrophic rhinitis, surgical interventions on a meninx (in the anamnesis), pregnancy, the lactation period, children's age till 6th years — for 0,1% of solution (0,001 g/ml).

With care: coronary heart disease (stenocardia), a diabetes mellitus, a prostate hyperplasia, a hyperthyroidism, children's age up to 2 years — for 0,05% of solution (0,0005 g/ml).


Overdose:

Symptoms: strengthening of side effects. Treatment: symptomatic under observation of the doctor.


Storage conditions:

In the dry, protected from light place at a temperature not above 25 °C. To store in the place, unavailable to children. A period of validity - 3 years. Not to apply after a period of validity.


Issue conditions:

Without recipe


Packaging:

Drops nasal 0,0005 g/ml (0,05%) and 0,001 g/ml (0,1%). On 10 ml in bottles of colourless or light-protective glass, or polymeric bottles droppers. Each bottle together with  the application instruction in a pack from a cardboard. The investment in a pack of a pipette or a cover dropper is allowed.



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