Hemolitic anemia

Description:

Hemolitic anemia (Latin anemia haemolytica from other - Greek αἷμα — "blood",  — "destruction", dissolution and anemia) — the group name of enough seldom found diseases which general symptom is the strengthened destruction of erythrocytes causing, on the one hand, anemia and the increased formation of decomposition products of erythrocytes, on the other hand — reaktivno the strengthened erythrogenesis.

Symptoms of Hemolitic anemia:

Increase in decomposition products of erythrocytes is clinically shown by jaundice of a lemon shade, increase in content in blood of the indirect (not conjugated) bilirubin (hyperbilirubinemia) and serumal iron, pleyokhromiy bile and a calla, an urobilinuria. At an intravascular hemolysis there are dobavochno a hypergemoglobinemia, a haemoglobinuria, a gemosiderinuriya. Strengthening of an erythrogenesis is demonstrated by a reticulocytosis and a polychromatophilia in peripheral blood, эритронормобластоз marrow.

Reasons of Hemolitic anemia:

The etiology of hemolitic anemia of a polimorfn - its nature can be hereditary (it is connected with a membranopathy, a hemoglobinopathy or an enzymopathy), acquired (immunohemolitic, toxic, mechanical damages of erythrocytes), mixed.

Treatment of Hemolitic anemia:

Apply to treatment of hemolitic anemia:
  1. splenectomy
  2. glucocorticosteroids at autoimmune hemolitic anemias in average doses
  3. immunodepresant
  4. a transfusion of erythrocytes at hemolitic crises, the washed erythrocytes which are individually picked up are necessary
  5. at increase in level of iron it is necessary to remove it - desferal
If antibodies at hemolitic anemia are active only at a low temperature — they are called cold if they are active at body temperature — thermal.