Etamsylate

General characteristics. Structure:

Active ingredient: etamsylate of 250 mg.

Pharmacological properties:

Antihemorrhagic means. Normalizes permeability of a vascular wall, improves microcirculation. Action is connected, apparently, with the activating influence on thromboplastin formation. Does not influence a prothrombin time, has no hypercoagulative properties and does not promote formation of blood clots.
The beginning of action - in 5-15 min. after in/in injections, the maximum effect - in 1-2 h after introduction. Action duration - 4-6 h.

Pharmacokinetics. About 72% of the entered dose are removed with urine during the first 24 h in not changed look. T1/2 later in/in introductions about 2 h.
Gets through a placental barrier, it is allocated with breast milk.

Indications to use:

Prevention and treatment of capillary bleedings at diabetic angiopatiya, at operative measures in otolaryngologic practice, in ophthalmology, stomatology, urology, in surgery and gynecology; emergencies at intestinal and pulmonary bleedings, at hemorrhagic diathesis.

Route of administration and doses:

At intake - on 250-500 mg 3-4, in oil or in/in - on 125-250 mg 3-4 If necessary it is possible to increase a single dose for intake to 750 mg, for parenteral administration to 375 mg.
To children - 10-15 mg/kg/, frequency rate of use - 3 in equal doses.
At external use the sterile tampon impregnated with etamsylate (in the form of solution for injections), is imposed on a wound.

Features of use:

With care at patients with thromboses or embolisms in the past.

Side effects:

Heartburn, feeling of weight in an anticardium, a headache, dizziness, a hyperemia of the person, decrease in the systolic ABP, paresthesia of the lower extremities are possible.

Interaction with other medicines:

Pharmaceutical it is incompatible with other medicines.

Contraindications:

Fibrinferments, thromboembolisms, hypersensitivity to etamsylate.
Etamsylate cannot be applied as the only means in the presence at the patient of the hemorrhages caused by anticoagulants.

Use for children
Use is possible according to the dosing mode.

Overdose:

There are no data.

Storage conditions:

In the dry, protected from light place.
To store in the place, unavailable to children.

Issue conditions:

Without recipe

Packaging:

Tablets of 250 mg; bottle (bottle) plastic 50.