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Мезим® forte

Препарат Мезим® форте. Berlin-Chemie AG/ Menarini Group (Берлин-Хеми АГ/ Менарини Групп) Германия


Producer: Berlin-Chemie AG/Menarini Group (Berlin-Hemi AG/Menarini Group) Germany

Code of automatic telephone exchange: A09AA02

Release form: Firm dosage forms. Tablets.

Indications to use: Preparation to radiological and to ultrasound examination of abdominal organs. Diarrhea. Meteorism. Liver diseases. Diseases of bilious ways. Mucoviscidosis. Chronic pancreatitis. Insufficiency of vneshnesekretorny function of a pancreas. Digestive tract diseases.


General characteristics. Structure:

Pancreatinum from minimum:

lipolytic activity - 3 500 PIECES of Ph.Eur.
amylolytic activity - 4 200 PIECES of Ph.Eur.
the general proteolytic activity - 250 PIECES of Ph.Eur.

Excipients:

Cellulose microcrystallic, carboxymethylstarch sodium salt (type A), silicon dioxide colloid, magnesium stearate.

Cover. Talc, gipromelloz, azoruby varnish (Е 122), симетикон emulsion of 30% (dry weight), polyacrylate dispersion of 30% (dry weight), titanium dioxide (Е 171), macrogoal 6000.




Pharmacological properties:

Drug compensates insufficiency of vneshnesekretorny function of a pancreas.

The enzymes which are a part of Pancreatinum the lipase, amylase and protease facilitate digestion of fats, carbohydrates and proteins that promotes their fuller absorption in a small intestine.


Indications to use:

• Insufficiency of vneshnesekretorny function of a pancreas, (chronic pancreatitis, mucoviscidosis and so forth).
• Chronic inflammatory and dystrophic diseases of a stomach, intestines, liver, gall bladder. The states after a resection or radiation of these bodies which are followed by disturbances of digestion of food, a meteorism, diarrhea (as a part of a combination therapy).
• For improvement of digestion of food at patients with normal function of digestive tract in case of errors in food.
• Preparation to radiological and to ultrasound examination of abdominal organs.


Route of administration and doses:

The dose is defined individually depending on extent of disturbance of digestion.

Adults: on 1-2 tablets before food, without chewing and washing down with water.

If necessary in addition during food accept still 1-4tabletka.

At children drug is used on doctor's orders.

Duration of treatment can vary of several days (at disturbance of process of digestion owing to errors in a diet) up to several months or years (in need of continuous replacement therapy).



Side effects:

Allergic reactions, diarrhea or lock, nausea, discomfort in epigastric area. At prolonged use in high doses development of a hyper uricosuria, increase in level of uric acid in a blood plasma is possible. In isolated cases at the patients suffering from a mucoviscidosis formation of strictures in ileocecal area after reception of high doses is observed.


Interaction with other medicines:

At simultaneous use of Pancreatinum with iron preparations decrease in absorption of the last is possible. Simultaneous use of antiacid means, calciferous a carbonate and/or magnesium hydroxide, can lead to decrease in efficiency of Pancreatinum.


Contraindications:

Hypersensitivity to drug components, acute pancreatitis, an exacerbation of chronic pancreatitis.

Use at pregnancy and a lactation


Safety of use of Pancreatinum at pregnancy is studied insufficiently. Use is possible in cases when the expected advantage for mother exceeds potential risk for a fruit.



Storage conditions:

To store at a temperature not above 30 °C. To store in the place, unavailable to children! Period of validity 3 years. Not to apply after expiry date.


Issue conditions:

Without recipe


Packaging:

Tablets, coated.

On 20 tablets in the blister from a film of aluminum PVC / foil.

On 1, 2,4 or 5 blisters with the Application instruction in a cardboard pack.



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