Sangviritrin

General characteristics. Structure:

Active veshchestva:sangviritrin – 2 g.

Auxiliary 95% of a veshchestv:etanol – 315 ml, the water purified – before receiving 1000 ml of drug.

Pharmacological properties:

Sangviritrin possesses a wide range of antimicrobic activity, affecting gram-positive and gram-negative bacteria, drozhzhepodobny and mitselialny mushrooms. It is active concerning antibiotikorezistentny strains of microorganisms. In therapeutic doses works bacteriostatically. Suppression of a bacterial nuclease, disturbance of processes of permeability of cell walls of partitions of division, a nucleoid structure is the cornerstone of the mechanism of antimicrobic action of a sangviritrin.

Indications to use:

Sangviritrin apply as antimicrobic means with the preventive and medical purpose at children (including newborns and children of early age) and adults (including pregnant women in dorodovy and puerperal the periods).
As prophylactic: newborns for the prevention of pyoinflammatory diseases have skin and at surgical patients – for prevention of a wound fever.
As remedy: at infectious and inflammatory diseases of skin and mucous membranes of a bacterial and fungal etiology, including Candida albicans; in stomatology – at a periodontal disease, aphthous stomatitis, an ulcer and necrotic gingivostomatitis and other damages of a mucous membrane of an oral cavity; in otorhinolaryngology – at diseases of a middle ear and outside acoustical pass; in surgery – at the infected burns, it is long not healing wounds and ulcers; in gynecology – at an endocervicitis, a colpitis, a vaginitis, an erosion of a neck of uterus; in dermatology – at pyodermas, superficial zymonematoses, dermatomycoses, etc.

Route of administration and doses:

Outwardly and/or locally.
The newborn process skin folds of 0,2% vodno spirit solution of a sangviritrin 2 times a day during the first 5-6 days of life by means of a sterile cotton plug.
Treatment of a periodontal disease is carried out after removal of tooth deposits and a scraping of pathological gingival pockets. Enter into gingival pockets for 20 minutes thin turundas, plentifully moistened 0,2% aqueous-alcoholic or aqueous solution of Sangviritrin. Aqueous solution of drug is prepared just before use. For preparation of aqueous solution from 0,2% of aqueous-alcoholic solution it is parted by 40 times (1 teaspoon on 200 ml of warm boiled water). The procedure is repeated daily or every other day. The course of treatment makes 4-6 procedures.

At stomatitises of various etiology on the centers of damage of a mucous membrane of an oral cavity 2-3 times a day within 2-5 days make drug solution application. To children 5 years are more senior appoint rinsings warm aqueous solution. To children 5 years at stomatitis are younger a mucous membrane of an oral cavity grease with aqueous solution.

At quinsies of an almond process 0,2% aqueous-alcoholic solution of Sangviritrin of 1 times a day within 2-5 days. Besides, to adults and children 5 years are more senior, daily 3-5 times a day appoint rinsing warm aqueous solution. To children up to 5 years with this solution 3-4 times a day grease a mucous membrane of an oral cavity. Duration of a course of treatment is 3-7 days.

At outside otitis enter into acoustical pass turundas, the moistened 0,2% aqueous-alcoholic solution of Sangviritrin for 10-15 minutes, 2-3 times a day. Minimum course of treatment two weeks. At chronic purulent average otitis of 0,2% aqueous-alcoholic solution of Sangviritrin is dug in the adult on 5-8 drops, to children – on 1-2 drops 3-4 times a day.

For prevention of pyoinflammatory complications daily the wound is processed the sterile gauze tampon which is plentifully moistened 0,2% with aqueous-alcoholic solution of Sangviritrin, covered with the sterile napkin moistened with the same solution and apply a retentive bandage. In 3-4 days the wound is processed by 0,2% aqueous-alcoholic solution of drug and apply a dry sterile bandage. The course is defined by the term of a wound repair and at an uncomplicated current the term of use makes 7-10 days.

For treatment of the infected burn, it is long not healing wounds and ulcers open of the infected changes, etc. apply aqueous solution of Sangviritrin. Aqueous solution of drug wash out wounds and ulcers, and also apply bandages with solution a wound surface. At the infected burns of bandaging make every other day, at other wounds – daily 1-2 times a day. Duration of treatment depends on character and disease severity.

At an endocervicitis, a colpitis, a vaginitis, erosion of a neck of uterus carry out syringings, irrigations and lotions by warm aqueous solution of Sangviritrin daily 1-2 times a day. The course of treatment makes 5-10 procedures.

At the pyodermas, a superficial zymonematosis and dermatomycoses including complicated by the mixed flora 0,2% appoint aqueous-alcoholic solution of Sangviritrin in the form of bandages or greasings of the center of defeat daily 1-2 times a day. Duration of treatment is defined by character and disease severity.

Features of use:

Not to allow hit of drug on mucous membranes of eyes. At hit of solutions of Sangviritrin in eyes it is necessary to wash out their large number waters.
At it is long not healing wounds and ulcers, an endocervicitis, colpitis, vaginitis, erosion of a neck of uterus, pyodermas, a superficial zymonematosis and dermatomycoses including complicated by the mixed flora, perhaps combined use of solutions of Sangviritrin in combination with linimentum of a sangviritrin (1% or 0,5%) which is appointed in the form of bandages or greasings of the center of defeat.

Side effects:

Local allergic reactions (dermahemia).
When rinsing or greasing by aqueous solutions of a sangviritrin of mucous membranes of an oral cavity – feeling of bitterness in a mouth, and at Sangviritrin's use on a wound surface – a short-term burning sensation. In these cases drug is used in lower concentration.

Interaction with other medicines:

Use in combination with mestnoanesteziruyushchy means is possible (промекаин, Trimecainum, etc.).

Contraindications:

Hypersensitivity to drug components, fungal infections with the eczematization phenomena. Diseases of a liver and kidneys with dysfunction.

Overdose:

When using drug in the doses exceeding recommended strengthening of side effects of drug is possible. Treatment: symptomatic therapy.

Storage conditions:

List B. In the dry, protected from light place at a temperature not above 25 °C.
To store in the place, unavailable to children.

Issue conditions:

Without recipe

Packaging:

Solution of 0,2% for external and topical administration (spirit) on 10, 25 and 50 ml in the bottles of dark glass enclosed together with the application instruction in cardboard packs.