DE   EN   ES   FR   IT   PT Medicines Antiseptic agent + mestnoanesteziruyushchy means. Anti-quinsies Formula spray

Anti-quinsies Formula spray

Препарат Анти-Ангин Формула спрей. Natur Produkt Europe B.V. (Натур Продукт Европа Б.В.) Нидерланды

Producer: Natur Produkt Europe B.V. (Natures Product Europe B.V.) Netherlands

Code of automatic telephone exchange: R02AA20

Release form: Liquid dosage forms. Spray.

Indications to use: Pharyngitis. Tonsillitis. Quinsy (Acute tonsillitis). Periodontosis. Stomatitis. Ulitis. Extraction of tooth. Pharyngalgia.

General characteristics. Structure:

Active agents:

Hlorgeksidina биглюконат                                      0,24 mg / 0,120 g
in the form of 20% of solution of a hlorgeksidin of a biglyukonat     of 1,20 mg / 0,600 g
Pantocain hydrochloride                                         of 0,12 mg / 0,060 g.

Excipients: глицерол 85% – 60,00 mg / 30,00 g, ethanol of 96% – 80,00 mg / 40,00 g, aspartame – 0,20 mg / 0,10 g, fragrance mint – 2,00 mg / 1,00 g, пропилпарагидроксибензоат – 0,20 mg / 0,10 g, anhydrous citric acid – 0,02 mg / 0,01 g, the water purified – to 200 mg / to 100 g.

Pharmacological properties:

Hlorgeksidin can have bactericidal and bacteriostatic effect.
Possesses a wide antibacterial range of action concerning gram-positive and gram-negative bacteria, it is active concerning Candida albicans. Hlorgeksidin is especially active concerning Streptococcus mutans, Streptococcus salivarius, Escherichia coli and anaerobic bacteria. Is less effective concerning such species of microorganisms as Streptococcus spp., Proteus spp., Pseudomonas, Klebsiella spp., Veillonella spp.
Pantocain has mestnoanesteziruyushchy effect.

Pharmacokinetics. Pantocain is easily and completely absorbed through mucous membranes. Linkng with proteins of plasma high. It is completely hydrolyzed by cholinesterase during 1-2 h with formation of compounds of para-aminobenzoic acid. It is removed by kidneys and with bile, at the same time partially is exposed to hepatoenteric recirculation.

There are no clinical data on absorption of a hlorgeksidin through a mucous membrane of an oral cavity of the person. Hlorgeksidin can remain in saliva to 8 h. Practically it is not soaked up from digestive tract. It is removed generally through intestines (90%), less than 1% are allocated with kidneys.

Indications to use:

Prevention, etiotropic and symptomatic treatment of the infectious and inflammatory diseases of an oral cavity and throat caused by microorganisms, sensitive to a hlorgeksidin (pharyngitis, tonsillitis, an initial stage of quinsy, periodontosis, stomatitis, an ulitis, a state after a tonsilectomy or extraction of tooth, etc.). Complex therapy of quinsy (to apply at the first symptoms of a disease – at a pharyngalgia and irritation).

Route of administration and doses:

Locally. Drug is sprayed on a mucous membrane of an oral cavity and a throat at breath holding.

Adults and children are more senior than 15 years: on 1-2 injections on reception to 6 times a day.
Children from 10 to 15 years: on 1-2 injections on reception to 3 times a day.
Course of treatment no more than 5 days.

Features of use:

Spray should not be inhaled. It is necessary to avoid hit of drug in eyes.
If in 3 days after an initiation of treatment symptoms of a disease do not disappear or deterioration in a course of a disease is observed, it is necessary to define expediency of its further use.
Children can use drug from 10 years, at the same time the child has to be capable to hold the breath at drug injection.
At administration of drug it is necessary to consider that 1 dose (1 injection) contains 83 mg of absolute ethanol.

Drug should be accepted not later than 30 min. prior to driving. At observance of this recommendation drug does not influence ability to driving of motor transport and control of mechanisms.

It is not recommended to apply along with the drugs for treatment of an oral cavity and a throat containing iodine (Lugol solution, povidone-iodine).

Side effects:

Allergic reactions, burning of a mucous membrane of an oral cavity.

Interaction with other medicines:

Sucrose, polysorbate 80, insoluble salts of magnesium, zinc and calcium reduce action of a hlorgeksidin.

Pantocain reduces antibacterial activity of sulfanamide drugs. Vasoconstrictors prolong effect and reduce toxicity. The medicines inhibiting cholinesterase (anti-myasthenic means, cyclophosphamide, Thiotepum, etc.), reduce metabolism of pantocain and increase its toxicity. Anticoagulants (далтепарин sodium, эноксапарин sodium, heparin sodium, warfarin) increase risk of development of bleedings. When using pantocain with the medicines inhibiting monoamine oxidase (furasolidone, Procarbazinum, селегилин), the risk of a lowering of arterial pressure increases. Pantocain strengthens and extends effect of myorelaxation medicines. Beta adrenoblockers slow down pantocain metabolism, increasing its toxicity (decrease in a hepatic blood-groove).


Hypersensitivity to drug components, damage or an inflammation of mucous membranes, in vysokovaskulyarizirovanny areas, a fenilketonuriya, children's age (up to 10 years).

With care: at pregnancy and in the period of a lactation, a diabetes mellitus, deficit glyukozo-6-fosfatdegidrogenazy, hemochromatosis, sideroblastny anemia, a thalassemia, a hyperoxaluria, an oxarod and an urolithiasis.
Use during pregnancy and a lactation: only after consultation with the doctor.


Overdose symptoms: dizziness, general weakness, cyanosis, excitement, concern, muscular tremor, breath disturbance, nausea, vomiting.
Treatment: gastric lavage, purpose of salt laxatives; symptomatic therapy.

Storage conditions:

at a temperature not above 25 °C. To store in the place, unavailable to children!

Issue conditions:

Without recipe


Spray for topical administration dosed.
On 25 ml of drug (100 doses) place in a plastic bottle with the valve of the dosing action in a cardboard pack with the application instruction.

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