Форлакс for children

General characteristics. Structure:

Active agent: macrogoal 4000 (polyethyleneglycol 4000) of 4 g

Excipients: a fragrance with a smell of orange and grapefruit (orange oil, grapefruit oil, the orange juice concentrated, citral, acetic aldehyde, linalol, ethyl butyrate, α-terpineol, octanal, cis-3 - гексенол, maltodextrin, acacias gum, sorbitol) - 60 mg, sodium saccharinate - 6.8 mg.

Pharmacological properties:

Osmotic laxative drug. The big molecular mass of a macrogoal 4000 is caused by long linear polymers which hold water molecules by means of hydrogen bindings. Thanks to it after oral administration of drug the volume of intestinal contents increases. The volume of not absorbed liquid which is in an intestines gleam supports laxative action of solution.
Laxative action of Forlaks comes in 24-48 h after reception.

Pharmacokinetics. Pharmacokinetic data confirm that at intake the macrogoal 4000 is not exposed to either gastrointestinal absorption, or biotransformation.

Indications to use:

— a symptomatic treatment of locks at children aged from 6 months up to 8 years.

Route of administration and doses:

To children aged from 6 months till 1 year appoint 1 package/days; from 1 year to 4 years - 1-2 packages/days; from 4 to 8 years - 2-4 packages/days.
Contents of 1 package should be dissolved approximately in 50 ml of water and to accept inside in the morning (at a dose of 1 package/days), or in the morning and in the evening (at a dose more than 1 package/days).
Treatment duration - no more than 3 months.
It is reasonable to support drug treatment of locks by the diet rich with a cellulose, and adequate physical activity.
If symptoms of a lock remain more than 3 months, it is necessary to conduct repeated expanded diagnostic examination.

Features of use:

Prior to therapy it is necessary to exclude organic gastrointestinal diseases.

Treatment of locks by means of medicines is recommended only as addition to a healthy lifestyle and a diet, for example: increase in consumption of liquids and cellulose; adequate physical activity which promotes recovery of motility of a GIT.

In case of development of diarrhea with extra care it is necessary to treat the patients predisposed to disturbances of water and electrolytic balance (for example, at patients with an abnormal liver function or kidneys, or the patients receiving diuretics); in such cases it is necessary to control the content of electrolytes.

There are messages on aspiration cases at introduction of large volumes of polyethyleneglycol with electrolytes via the nazogastralny probe. The children suffering from neurologic frustration with swallowing disturbance are especially subject to risk of aspiration.

Very exceptional cases of hypersensitivity (including rash, urticaria, hypostasis) at administration of drugs were registered, containing a macrogoal (polyethyleneglycol). The acute anaphylaxis was in exceptional cases observed.

Форлакс® contains sorbitol therefore drug should not be used at patients with inborn intolerance of fructose.

Форлакс® does not contain a large amount of sugar or polyol therefore it is possible to appoint drug a sick diabetes mellitus, and also to patients whose of diet the galactose is excluded.

Side effects:

Determination of frequency of side reactions: very often (≥1/10), it is frequent (≥1/100-<1/10), infrequently (≥1/1000-<1/100), is rare (<1/1000), is very rare (≥1/10 000).
Generally undesirable reactions have easy passing temper and are most often connected with disorders of a GIT.
From the alimentary system: often - abdominal pain, diarrhea (can cause irritation of perianal area); infrequently - nausea, vomiting, a meteorism.
Experience of use of drug in routine practice: very seldom - hypersensitivity reactions * in the form of rash, a small tortoiseshell, a Quincke's edema.
* information is provided on the basis of the data collected for all drugs containing a macrogoal in various dosages.

Interaction with other medicines:

Форлакс® slows down absorption of at the same time accepted medicines. Therefore it is recommended to appoint it not earlier than in 2 h after reception of other drugs.

Contraindications:

— serious inflammatory diseases of intestines (ulcer colitis, disease Krone);
— toxic megacolon;
— perforation or risk of perforation of a gut;
— full or partial intestinal obstruction, suspicion on intestinal impassability, a symptomatic stenosis;
— abdominal pains of not clear etiology;
— hypersensitivity to a macrogoal (polyethyleneglycol) or other components of drug.

Use for children
To children aged from 6 months till 1 year appoint 1 package/days; from 1 year to 4 years - 1-2 packages/days; from 4 to 8 years - 2-4 packages/days.

Overdose:

Symptoms: diarrhea which stops at reduction of a dose of drug or its cancellation is possible; intensive diarrhea or vomiting can cause disturbance of water and electrolytic balance that will demand its correction; there are messages on emergence of an inflammation and irritation of perianal area and an incontience a calla in cases of use of polyethyleneglycol in large volumes (4-11 l) for the purpose of cleaning of intestines before a kolonoskopiya.

Storage conditions:

Drug should be stored in the place, unavailable to children, at a temperature not above 30 °C.

Issue conditions:

Without recipe

Packaging:

Powder for пригот. solution for intake (for children) 4 g: bags of 20 pieces.