Гриппостад® Rino

General characteristics. Structure:

Active agent: xylomethazolinum a hydrochloride - 1 mg; excipients: a benzalkoniya of chloride of 50% solution, citric acid monohydrate, sodium citrate a dihydrate, glycerin of 85% (глицерол), the water purified. Transparent, colourless to slightly painted solution, free from visible foreign particles, inodorous.

Pharmacological properties:

Pharmacodynamics. Xylomethazolinum - derivative imidazoline, is an alfa2-adrenostimulyator. Narrows blood vessels of a mucous membrane of a nasal cavity therefore hypostasis and a hyperemia of a mucous membrane decreases. Facilitates nasal breath at rhinitises. Action comes in 5-10 minutes and continues till 10 o'clock. Does not break function of a ciliate epithelium mucous respiratory tracts.

Pharmacokinetics. At topical administration it is practically not soaked up, concentration in plasma are so small that they cannot be determined by modern analytical methods.

Indications to use:

Acute allergic rhinitis, acute respiratory diseases with the rhinitis phenomena, sinusitis, a pollinosis; average otitis (for reduction of hypostasis of a mucous membrane of a nasopharynx). Training of the patient for diagnostic manipulations in the nasal courses.

Route of administration and doses:

Intranazalno. Drops for a nose for adults and children are more senior than 6 years - on 2-3 drops of 0,1% of solution, there is usually enough 4 times a day. It is not necessary to apply more than 4 times a day. Гриппостад® Rino should not be used longer, than 5 days, except for the cases ordered by the doctor. Reuse of drug is possible in several days. Duration of therapy is determined by the doctor.

Features of use:

Before use it is necessary to clear the nasal courses. It is not necessary to apply for a long time, for example at chronic rhinitis.

Side effects:

At frequent and/or prolonged use - irritation and/or dryness of a mucous membrane of a nasopharynx, burning, paresthesias, sneezing, hypersecretion. Seldom - hypostasis of a mucous membrane of a nasal cavity, heartbeat, tachycardia, arrhythmias, increase in arterial pressure, a headache, vomiting, sleeplessness, a vision disorder; a depression (at prolonged use in high doses).

Interaction with other medicines:

It is incompatible with inhibitors of a monoaminooxidase and tricyclic antidepressants.

Contraindications:

Hypersensitivity to drug components, arterial hypertension, tachycardia, the expressed atherosclerosis, glaucoma, atrophic rhinitis, a thyrotoxicosis, surgical interventions on a meninx (in the anamnesis), pregnancy, children's age (up to 6 years).

With care to apply at a diabetes mellitus, a pheochromocytoma, coronary heart disease (stenocardia), a prostate hyperplasia, in the period of a lactation.

Overdose:

At the correct use of drug the overdose of drug is impossible since drug at topical administration is practically not soaked up. However at exceeding of the recommended doses strengthening of side effects several times is observed. Treatment: symptomatic.

Storage conditions:

At a temperature not over 25 to °s.khranit in the place, unavailable to children.

Issue conditions:

Without recipe

Packaging:

Гриппостад® Rino, drops nasal 0,1% solution. On 10 ml in bottles from glass of amber color with the polypropylene screwing-up cover supplied with a pipette. Each bottle with the instruction on a medical use of drug is placed in a cardboard pack.