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Corvalol N

Препарат Корвалол Н. ОАО "Фармак" Украина

Producer: JSC Pharmak Ukraine

Code of automatic telephone exchange: N05CB02

Release form: Liquid dosage forms. Drops for oral administration.

Indications to use: Intestinal colic. Neurosis. Arterial hypertension. Vegeto-vascular dystonia. Tachycardia. Spasm of blood vessels (vasomotor spasm).

General characteristics. Structure:

Active ingredient: acid a-bromizovalerianovoy ethyl ether, menthol solution in mentilovy ether of isovaleric acid, mint oil, hop oil;

1 ml of solution (25 drops) contains acid a-bromizovalerianovoy ethyl ether in terms of 100% substance of 20 mg, menthol solution in mentilovy ether of isovaleric acid of 55 mg; mints of oil of 1,42 mg; oils of hop of 0,2 mg;

excipients: sodium acetate trihydrate, the acetic acid divorced ethanol (96%), the water purified.

Pharmacological properties:

Корвалол®Н - the calming and spasmolytic drug which effect as complex drug is defined by the components which are its part.

Ethyl ether of α-bromizovalerianovy acid has the reflex calming and spasmolytic effect caused by irritation preferential of receptors of an oral cavity and a nasopharynx, decrease in reflex irritability in the central parts of the nervous system and strengthening of the phenomena of braking in neurons of bark and subcrustal structures of a brain and also decrease of the activity of the central vasomotor centers and direct local spasmolytic action on smooth muscles of vessels.

Validol or solution of menthol in mentilovy ether of isovaleric acid renders sedative, and also moderate coronarodilator effect due to impact on sensitive nervous receptors of a mucous membrane of an oral cavity.

Oil of mint contains a large amount of essential oils, including about 50% of menthol and 4-9% of ethers of menthol. They are capable to irritate "cold" receptors of an oral cavity and to reflex expand preferential vessels of heart and brain, removing spasms of smooth muscles, causing the calming and easy cholagogue action. Oil of a peppermint possesses antiseptic, spasmolytic action, ability to eliminate the meteorism phenomena. Irritating receptors of a mucous membrane of a stomach and intestines, strengthens an intestines peristaltics.

Oil of hop has reflex vasodilating and spasmolytic effect, eliminates the meteorism phenomena.

At intake absorption of drug begins already with a mucous membrane of an oral cavity. Action develops 15-45 minutes later and lasts for 3-6 h.

Indications to use:

Neurosises with an acrimony;
in complex therapy of arterial hypertension and vegeto-vascular dystonia;
unsharply expressed spasms of coronary vessels, tachycardia;

Route of administration and doses:

Корвалол®Н accept inside irrespective of meal 2-3 times a day till 15-30 of drops with water or on a sugar piece. If necessary (the expressed tachycardia and a spasm of coronary vessels) the single dose can be increased till 40-50 drops.

Duration of use of drug is determined by the doctor depending on clinical effect and portability of drug.

Features of use:

Use during pregnancy and feeding by a breast.

Not to apply during pregnancy and during feeding by a breast.

Ability to influence speed of response at control of motor transport or work with other mechanisms.

Drug contains 58 about. % of alcohol which can cause a lack of coordination and speeds of psychomotor reactions therefore at administration of drug the persons working with difficult mechanisms, to drivers of motor transport   , etc. should be careful.

Children. There is no experience of use for treatment of children.

Side effects:

Корвалол®Н, as a rule, it is well transferred. In some cases such side effects can be observed:

from a nervous system: drowsiness, slight dizziness, decrease in concentration of attention;

from the alimentary system: nausea;

from immune system: allergic reactions;

others: dacryagogue.

These phenomena are eliminated with reduction of a dose.

At prolonged use emergence of dependence on drug and the phenomenon of a bromism is possible: drowsiness, apathy, rhinitis, conjunctivitis, incoordination, confusion of consciousness, acne.

Interaction with other medicines:

The drugs oppressing the central nervous system strengthen action of Korvalola®H.

Корвалол®Н strengthens sedation of psychotropic drugs, opioid analgetik, alcohol and anesthetics.

Perhaps potentsiirovany effects of anti-hypertensive drugs at their simultaneous use with Korvalolom®H.

Alcohol strengthens effect of drug.


Hypersensitivity to drug components, bromine;
the expressed arterial hypotension;
the expressed abnormal liver functions and/or kidneys;
heavy heart failure;
pregnancy and feeding by a breast.

Necessary security measures at use


It is necessary to avoid the simultaneous use of alcoholic drinks.

Prolonged use of drug in connection with possible formation of dependence on drug is not recommended.

It is careful to appoint drug at arterial hypotension.


The overdose is possible at frequent or prolonged use of drug that it is connected with cumulation of its components. Prolonged and constant use causes dependence, an abstinence syndrome, psychomotor excitement.

Symptoms: oppression of the central nervous system, sleep disorder, lowering of arterial pressure, apathy, rhinitis, conjunctivitis, incoordination, confusion of consciousness, acne.

Symptomatic treatment.

Storage conditions:

Period of validity 2 years and 6 months. Not to use drug after the termination of the period of validity specified on packaging. To store in the place protected from light at a temperature not over 25 ºС. To store in the place, unavailable to children.

Issue conditions:

Without recipe


On 25 ml in the bottle enclosed in a pack.

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