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medicalmeds.eu Medicines Complexing means. Унитиол-Ферейн®

Унитиол-Ферейн®

Препарат Унитиол-Ферейн®. ЗАО "Брынцалов-А" Россия



General characteristics. Structure:

Active ingredient: 0,05 g of Unithiolum in 1 ml of solution.

Excipients: water for injections.

Complexing means, has disintoxication effect.




Pharmacological properties:

Pharmacodynamics. Active sulphhydryl groups of Unithiolum, interacting with thiol poisons (compound of arsenic, salt of heavy metals) and forming with them non-toxic, water-soluble connections, recover functions of the fermental systems of an organism struck with poison. At diabetic polyneuropathy reduces a pain syndrome, improves a condition of a peripheral nervous system and normalizes permeability of capillaries.

Pharmacokinetics. At parenteral administration it is quickly soaked up in blood. The maximum level of drug in blood (Cmax) is reached in 15-30 min. after an injection in oil. Elimination half-life (T1/2) of-1-2 h. It is excreted by kidneys, mainly in the form of products of incomplete and full oxidation, partially - in an invariable look.


Indications to use:

Intoxication arsenic, mercury, bismuth, chrome, cardiac glycosides, hepatocerebral dystrophy (Wilson-Konovalov's disease), diabetic polyneuropathy, an alcoholism (as a part of complex therapy), a delirium.


Route of administration and doses:

Intramusculary, subcutaneously. At intoxication arsenic - 5-10 ml of drug (at the rate of 0,005 g / 1 kg), in the first days - 3-4 times, in the second sutyok - 2-3 times, in the subsequent - on 1-2 times.

At poisonings with compounds of mercury - according to the same scheme during 6-7 days. Treatment is carried out to disappearance of symptoms of intoxication.

At digitalis intoxication in the first 2 days 3-4 times a day, then 1 - 2 time a day before the termination of cardiotoxic action enter 5-10 ml of 5% of aqueous solution.

At hepatocerebral dystrophy - 5-10 ml of 5% in oil of solution daily or every other day; a course of treatment - 25-30 injections; if necessary repeat in 3-4 months.

At an alcoholism appoint 3-5 ml 2-3 times a week. For stopping of a delirium - once 4-5 ml of solution.


Features of use:

At acute poisonings along with administration of drug carry out a gastric lavage, an oxygenotherapy, administration of glucose, etc.


Side effects:

Nausea, dizziness, tachycardia, pallor of integuments. Allergic reactions are possible.


Interaction with other medicines:

Simultaneous use of Unithiolum with drugs which part heavy metals and alkalis since there is a bystry decomposition of Unithiolum are is not recommended.


Contraindications:

Hypersensitivity to drug, a liver failure; arterial hypertension.


Overdose:

In the recommended doses and according to indications of the phenomena of overdose does not arise.


Storage conditions:

Period of validity - 5 years. Not to apply after the period of validity specified on packaging. List B. In the place protected from light at a temperature not above 20 °C, in the place, unavailable to children.


Issue conditions:

According to the recipe


Packaging:

5% solution for intramuscular and hypodermic introduction in ampoules on 5 ml, on 5 ampoules in a blister strip packaging, on 1 or 2 planimetric packagings in a pack.



Similar drugs

Unithiolum

Detoksitsiruyushchy means. Antidotes.





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