Raccoon 400

General characteristics. Structure:

Active ingredient: D - alpha tocopheryl acetate; 1 capsule contains: 400 ME vitamins E (D - alpha tocopheryl acetate);

excipients: soy oil, gelatin, glycerin (85%).

Pharmacological properties:

Tocopherol in an organism increases protective properties of cellular membranes.

Tocopherol gets to blood, mainly, with a lymph, the maximum concentration in serum is reached in 4 - 8 hours after intake and in a day again is returned to the previous level. Tocopherol is emitted with bile. As concentration of a-tocopherol in bile is stable, unlike concentration in serum, sharp fluctuations of concentration of vitamin E in plasma are not reflected directly in bile.

Indications to use:

Drug is appointed in complex therapy of infertility as auxiliary therapy at disturbances of a menstrual cycle.

Drug is used as supportive application if there are signs of deficit of vitamin E in therapy of diseases of a digestive tract, muscular system, the joint device, neurologic diseases, dysfunctions of hemadens, at defective food, at liver diseases, at alimentary anemia, skin diseases, at neurosensory relative deafness, as a part of antioxidant therapy.

Route of administration and doses:

Doses select individually, depending on the nature of a disease. The average duration of use is from 1-3 weeks up to 2-3 months. If the doctor does not appoint differently, the adult to apply:

- at infertility, disturbances of a menstrual cycle (in combination with hormonal therapy) - on 400 mg every other day, repeating 5 times, since 17 in the afternoon a cycle;

- at rhematoid diseases - on 400 mg daily within several weeks;

- at primary muscular dystrophy to - 2000 mg a day, at other neurologic indications are enough 400 mg a day within 30 - 60 days;

- at alimentary anemias - on 400 mg a day within 10 days;

- at chronic hepatitises with aggravations appoint treatment with a daily dose of 400 mg within several months;

- at endocrinological diseases - on 400 mg a day;

- as the component of antioxidant therapy is applied on 400 mg of 1 - 2 time a day;

To children 12 years are more senior appoint 400 mg a day.

The capsule is swallowed entirely, washing down with enough neutral liquid.

Side effects:

Usually drug is well transferred, however at prolonged treatment or after reception of high doses the digestive disturbance, fatigue, weakness, a headache are in exceptional cases possible. Use of high doses of vitamin E can aggravate disturbances of coagulability of blood, caused by a lack of vitamin K.

Interaction with other medicines:

 Vitamin E facilitates absorption and digestion of vitamin A and prevents development of avitaminosis of A. V to a dose over 10 mg/kg a day vitamin E slows down therapeutic effect of iron at appointment to children with an iron deficiency anemia. With small body weight at the birth which appoint iron preparations deficit of vitamin E can cause hemolitic anemia in children.

Vitamin E or its metabolites have opposite effect of vitamin K. Long purpose of vitamin E can cause hemorrhages in patients who were treated by peroral anticoagulants.

There are data that vitamin E can increase efficiency of anticonvulsants at patients with epilepsy in whose blood the increased maintenance of products of peroxide oxidation of lipids is revealed.

Contraindications:

Patients cannot accept drug with hypersensitivity to any of drug components.

Special cautions. It is necessary to be careful at use
vitamin E patients with the expressed cardiosclerosis and at an acute myocardial infarction.

- Use during pregnancy or feeding by a breast. It can be applied during pregnancy and feeding by a breast only under careful observation of the doctor.

- Ability to influence speed of response at control of motor transport or other mechanisms. Does not influence.

- Children. Do not appoint to children aged up to 12 years in a dosage of 400 mg.

Storage conditions:

Period of validity. 3 years. To store in protected from light, the place, unavailable to children, at a temperature not above 25 °C.

Issue conditions:

Without recipe

Packaging:

On 3 blisters in a bag from a foil; on 1 bag in cardboard packaging.