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medicalmeds.eu Medicines Antispasmodic, M-cholinolytic. Driptan

Triptane

Препарат Дриптан. Solvay Pharmaceuticals, (Солвей Фармасьютикалз ) GmbH Германия


Producer: Solvay Pharmaceuticals, (Solvey Pharmasyyutikalz) GmbH Germany

Code of automatic telephone exchange: G04BD04

Release form: Firm dosage forms. Tablets.

Indications to use: Urine incontience. Detruzorno-sfinkternaya dyssynergia. Enuresis.


General characteristics. Structure:

Active agent: oksibutinina hydrochloride of 5 mg

Excipients: MKTs; calcium stearate; lactose anhydrous.




Pharmacological properties:

Pharmacodynamics. Weakens a detruzor (the muscle reducing a bladder). Renders direct spasmolytic myotropic and m-holinoblokiruyushchee action. Increases bladder capacity, reduces the frequency of reductions of a detruzor, constrains desires to an urination.

Pharmacokinetics. Cmax after intake is reached in 45 min. Concentration is proportional to the applied dose. T1/2 makes less than 2 h (increases at patients of advanced age).


Indications to use:

- the urine incontience connected with instability of the function of a bladder broken or as a result of disorders of neurogenic character (a detruzor hyper reflex), for example at a widespread sclerosis or spina bifida or at idiopathic dysfunctions of a detruzor (a motor incontience);

- night enuresis at children is more senior than 5 years.


Route of administration and doses:

Inside. The adult — on 5 mg 2–3 times a day, to children and patients of advanced age — on 5 mg 2 times a day.


Features of use:

Care is necessary at a renal failure and a liver, a hyperthyroidism, an ischemic heart disease, heart failure, arrhythmia, arterial hypertension, prostate adenoma, hernia of an esophageal opening of a diaphragm.


Side effects:

Nausea, lock, diarrhea, discomfort in abdominal area, an urination delay, drowsiness or sleeplessness, the general weakness, a headache, dizziness, arrhythmia, a vision disorder (a mydriasis, accommodation paralysis), increase in intraocular pressure, the lowered sweating, dryness in a mouth, impotence, allergic reactions.


Interaction with other medicines:

There are no data.


Contraindications:

- hypersensitivity to drug components;
- closed-angle glaucoma;
- obstruction of a GIT, intestines atony, expansion of a colon, ulcer colitis;
- myasthenia;
- obstructive uropathy;
- bleeding;
- feeding period breast;
- children's age up to 5 years.

Use at pregnancy and feeding by a breast
During pregnancy of Driptan® apply only according to strict indications. In need of use of drug in the period of a lactation it is necessary to resolve an issue of the breastfeeding termination.


Overdose:

Symptoms: excitement of TsNS (concern, a tremor, the increased nervous irritability, spasms, nonsense, hallucinations), fever, nausea, vomiting, tachycardia, decrease in the ABP, respiratory insufficiency, paralysis, a coma.

Treatment: it is necessary to support breath, to cause vomiting or to carry out a gastric lavage, to appoint absorbent carbon and salt laxative. For regression of symptoms of anticholinergic intoxication use blockers of cholinesterase (physostigmine). At the expressed concern or excitement — in/in introduction of 10 mg of diazepam. At tachycardia — propranolol (in/in).


Storage conditions:

At a temperature not above 30 °C.
To store in the place, unavailable to children.


Issue conditions:

According to the recipe


Packaging:

In the blister of 30 pieces; in a pack the cardboard 1 blister.



Similar drugs

Препарат Новитропан. Solvay Pharmaceuticals, (Солвей Фармасьютикалз ) GmbH Германия

Novitropan

Spasmolytic, myotropic means.





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