Компливит® Oftalmo

General characteristics. Structure:

Vitamin A (acetate Retinolum)	- 1,00 mg (2907 ME)
Vitamin E (acetate α-tocopherol)	- 15,00 mg
B1 vitamin (hydrochloride thiamin)	- 5,00 mg
B2 vitamin (Riboflavinum)	- 2,00 mg
B6 vitamin (hydrochloride pyridoxine)	- 5,00 mg
Vitamin C (ascorbic acid)	- 50,00 mg
Folic acid	- 400 mkg
Rutoside (Rutinum)	- 25,00 mg
B12 vitamin (cyanocobalamine)	- 3,00 mkg
Lyuteina	- 2,50 mg
Zeaxanthin (optisharp)	- 1,00 mg
Selenium (in the form of selenit sodium)	- 25,00 mkg
Copper (in the form of pentahydrate sulfate copper)	- 1,00 mg
Zinc (in the form of oxide zinc)	- 5,00 mg

Excipients:

Kernel: talc, potato starch, citric acid, лудипресс (lactoses monohydrate of 93%, povidone of 3,5%, кросповидон 3,5%), povidone low-molecular (polyvinylpirrolidone low-molecular), magnesium stearate, sucrose (sugar), D - sorbitol (sorbite food), a karmelloza of sodium (вивасол).

Cover: hypro rod (hydroxypropyl cellulose), macrogoal (poly(ethylene oxide)), povidone low-molecular (polyvinylpirrolidone low-molecular), titanium dioxide (E-171), talc, dye sunset yellow (E-110).

The excipients which are a part of substances of active agents:

Vitamin A:

[sucrose, the starch modified sodium-aluminum silicate, butyl hydroxytoluene, gelatin] or [butyl hydroxytoluene (VNT), gelatin, sucrose, starch corn];

Vitamin E:

[gelatin, sucrose, starch, sodium-aluminum silicate] or [the gelatin hydrolyzed silicon dioxide];

Luteinum:

[d, l - an alpha the tocopherol, starch modified syrup of a dextrose (glucose), sodium an ascorbate crystal, starch corn].

Zeaxanthin:

[d, l - an alpha the tocopherol, starch modified, sucrose, sodium an ascorbate crystal, starch corn].

Pharmacological properties:

The combined drug containing a complex of vitamins, microelements and vegetable carotinoids.

Pharmacological effect of drug is caused by properties of the components which are its part.

Compatibility of components in 1 tablet is provided with the production technology, special for vitamin drugs.

Ascorbic acid (vitamin C) – regulates permeability of capillaries, plays an important role in preservation of their elasticity. Activates activity of hemadens, regulates coagulability of blood, an angenesis, formation of steroid hormones, collagen synthesis. Exerts the stimulating impact on an organism in general, raises its adaptation opportunities, resilience to infections and adverse effects.

Thiamin _{(B1 vitamin)} – participates in process of transfer of an impulse on nerve fibril. Participates in coordination of functioning of nervous, cardiovascular, endocrine systems. Plays a key role in ensuring normal course of power metabolism.

Riboflavinum (B2 vitamin) – participates in carbohydrate, proteinaceous and fatty exchanges, in synthesis of hemoglobin and erythropoetin. It is necessary for maintenance of normal visual function.

The pyridoxine _{(B6 vitamin)} – as a coenzyme takes part in metabolism of amino acids and carbohydrates. Provides normal functioning of the central and peripheral nervous system.

Folic acid – in the form of a coenzyme joins in various metabolic processes necessary for synthesis of nucleic acids. Has antianemic effect, raises a tromborezistentnost of an endothelium and warns an obliteration of vessels.

Cyanocobalamine _{(B12 vitamin)} – participates in synthesis of nucleotides, is an important factor of a hemopoiesis and normal growth of epithelial cells; it is necessary for metabolism of folic acid and synthesis of a myelin.

Rutoside (Rutinum) – participates in oxidation-reduction processes, has antioxidant properties, prevents oxidation and promotes deposition of ascorbic acid in fabrics. Strengthens walls of capillaries, regulating their permeability. Reduces puffiness and an inflammation, strengthens a vascular wall.

Retinolum (vitamin A) – as a component of a rhodopsin of rhodopsin is important in maintenance of visual function, provides normal activity of the visual analyzer and perception with light eye. It is effective at a hemeralopia ("night blindness"), diseases of a retina and a cornea. Participates in processes of regeneration of skin and mucous membranes.

α-tocopherol acetate (vitamin E) – has antioxidant properties, maintains stability of erythrocytes; exerts positive impact on functions of gonads, nervous and muscular tissue. Participates in processes of tissue respiration, influences function of hemadens, slows down processes of aging of body tissues.

Luteinum and zeaxanthin - the carotinoids, pigments of yellow color necessary for normal functioning of a retina of an eye. Protect an eye from the damage arising owing to influence of ultra-violet light. Are components of antioxidant system of a retina, one of the most important factors of protection of an eye. Luteinum and zeaxanthin which are in a crystalline lens and a retina provide protection of photoreceptors of cells against the oxygen radicals which are formed at adverse effects approximately of the radiation of various origin. The low maintenance of Luteinum and zeaxanthin in an eye defines predisposition to various eye diseases and leads to easing of ability of an eye to resist adverse factors, long visual loadings, computer radiation.

Selenium - natural antioxidant, increases immunity. In combination with vitamins A, E and C has the expressed antioxidant effect, improves adaptation abilities of an organism in the conditions of influence of adverse factors (a stress, smoking, environmental pollution).

Copper – is the catalyst of many biochemical reactions. Participates in melanin synthesis. Plays an essential role in formation of collagen and elastin, is a necessary component of exchange of iron, plays an important role in the course of a hemopoiesis.

Zinc - promotes vitamin A utilization by a retina. Prevents development of a hemeralopia ("night blindness"). Zinc is necessary for synthesis of insulin, hormones of gonads, is necessary for normal activity of an adenoid tissue. Deficit of zinc is connected with development of retrobulbar neuritis, a blepharitis, decrease in color perception, formation of a cataract.

As a result drug provides the balanced intake of the components necessary for maintenance of optimum performance of an organism has oftalmoprotektivny effect thanks to combined effect of the vitamins which are its part, minerals and carotinoids, improves sight at the raised visual loadings, has antioxidant effect (protects eye fabric from influence of free radicals). It can be recommended when carrying contact lenses since contains the components necessary for an angenesis including corneas which damage by contact lenses always happens in a varying degree.

Indications to use:

• prevention of a vitamin deficiency and minerals;
• syndrome of visual exhaustion (fatigue and eye pain) during the reading, work on the computer, carrying contact lenses; disturbances of twilight sight.

Route of administration and doses:

The adult inside after food, washing down with enough liquid. On 1 tablet once a day. Duration of a course is 3 months. Repeated courses according to the recommendation of the doctor.

Features of use:

Exceeding of the recommended dose is not recommended.
Perhaps, coloring of urine in rich yellow color that is caused by availability of Riboflavinum as a part of drug and does not constitute danger.

Side effects:

Allergic reactions are possible.

Interaction with other medicines:

The concomitant use with other polyvitaminic complexes containing vitamins A and E, group B vitamins is not recommended.

Contraindications:

Individual intolerance of components of drug, pregnancy, the lactation period, children's age up to 18 years.

Overdose:

At overdose it is necessary to see a doctor.
Treatment: absorbent carbon inside, gastric lavage, symptomatic treatment.

Storage conditions:

In the dry place protected from light at a temperature not over 25 ºС. To store in and the place, unavailable to children.

Period of validity - 2 years. Not to use after a period of validity.

Issue conditions:

Without recipe

Packaging:

Tablets, film coated.
On 30, 60, 90, 100,120 tablets in banks polymeric. Banks cork the covers screwed.
Each can together with the instruction on a medical use is placed in a pack from a cardboard.