Компливит®

General characteristics. Structure:

Active components:

Vitamin A (acetate Retinolum)	- 1,135 mg (3300 ME)
Vitamin E (acetate a-tocopherol)	- 10,00 mg
B1 vitamin (hydrochloride thiamin)	- 1,00 mg
B2 vitamin (Riboflavinum mononucleotide)	- 1,27 mg
B6 vitamin (hydrochloride pyridoxine)	- 5,00 mg
Vitamin C (ascorbic acid)	- 50,00 mg
Niacinamide	- 7,50 mg
Folic acid	- 100 mkg
Rutoside (Rutinum)	- 25,00 mg
Pantothenate calcium	- 5,00 mg
B12 vitamin (cyanocobalamine)	- 12,5 mkg
Thioctic acid (lipoic acid)	- 2,00 mg
Phosphorus (in the form of magnesium of hydrophosphate of trihydrate and in the form of dihydrate phosphate calcium)	- 60,00 mg
Gland (in the form of heptahydrate sulfate iron)	- 5,00 mg
Manganese (in the form of pentahydrate sulfate manganese)	- 2,50 mg
Copper (in the form of pentahydrate sulfate copper)	- 0,75 mg
Zinc (in the form of heptahydrate sulfate zinc)	- 2,00 mg
Magnesium (in the form of trihydrate hydrophosphate magnesium)	- 16,40 mg
Calcium (in the form of dihydrate phosphate calcium)	- 50,50 mg
Cobalt (in the form of heptahydrate sulfate cobalt)	- 0,10 mg

Excipients:
Kernel: talc, potato starch, citric acid, povidone low-molecular (polyvinylpirrolidone), calcium октадеканоат (calcium stearate), sucrose (sugar).
Cover: hypro rod (hydroxypropyl cellulose), macrogoal (poly(ethylene oxide)), povidone low-molecular (поливилпирролидон), titanium dioxide (E-171), talc, aspartame.

Description
Tablets of biconvex oblong shape, film coated white color.

Pharmacological properties:

The combined drug containing a complex of the vitamins and minerals which are important factors of metabolic processes.

The vitamin and mineral complex is developed for completion of physiological need for vitamins and mineral substances in addition to a food allowance, balanced taking into account the daily need for vitamins and minerals. Compatibility of components in 1 tablet is provided with the production technology, special for vitamin drugs.

Vitamin A (Retinolum acetate) provides normal function of skin, mucous membranes, and also an organ of sight.

_{B1 vitamin} (thiamin a hydrochloride) as coenzyme participates in carbohydrate metabolism, functioning of a nervous system.

_{B2 vitamin} (Riboflavinum) the most important catalyst of processes of cellular respiration and visual perception.

_{B6 vitamin} (a pyridoxine a hydrochloride) as coenzyme takes part in protein metabolism and synthesis of neurotransmitters.

_{B12 vitamin} (cyanocobalamine) participates in synthesis of nucleotides, is an important factor of normal growth, a hemopoiesis and development of epithelial cells; it is necessary for metabolism of folic acid and synthesis of a myelin.

Niacinamide participates in processes of tissue respiration, fatty and carbohydrate metabolism.

Vitamin C (ascorbic acid) provides collagen synthesis; participates in formation and maintenance of structure and function of cartilages, bones, teeth; influences formation of hemoglobin, maturing of erythrocytes.

Rutinum (rutoside) participates in oxidation-reduction processes, has antioxidant properties, prevents oxidation and promotes deposition of ascorbic acid in fabrics.

Calcium pantothenate as a component of coenzyme A plays an important role in processes of acetylation and oxidation; promotes creation, regeneration of an epithelium and an endothelium.

Folic acid takes part in synthesis of amino acids, nucleotides, nucleic acids; it is necessary for a normal erythrogenesis.

Lipoic acid participates in regulation of lipidic and carbohydrate exchanges, renders lipotropic effect, influences cholesterol exchange, improves function of a liver.

Vitamin E (α-tocopherol acetate) has antioxidant properties, maintains stability of erythrocytes, prevents hemolysis; exerts positive impact on functions of gonads, nervous and muscular tissue.

Iron participates in an erythrogenesis, as a part of hemoglobin provides oxygen transport in fabric.

Copper warns anemia and air hunger of bodies and fabrics, promotes prevention of osteoporosis. Strengthens walls of vessels.

Calcium is necessary for formation of bone substance, a blood coagulation, implementation of process of transfer of nervous impulses, reduction of skeletal and unstriated muscles, normal activity of a myocardium.

Cobalt regulates metabolic processes, increases protective forces of an organism.

Manganese has antiinflammatory properties.

Zinc has immunomodulatory properties, promotes digestion of vitamin A, regeneration and growth of hair.

Magnesium contributes to normalization of arterial pressure, stimulates development of a calcitonin and parathyroid hormone together with calcium, prevents formation of stones in kidneys.

Phosphorus strengthens a bone tissue and teeth, strengthens a mineralization, is a part of ATP – an energy source of cells.

Indications to use:

• prevention and completion of a vitamin deficiency and mineral substances;
• the raised exercise and intellectual stresses;
• the recovery period after the long and/or hard proceeding diseases, including infectious;
• in complex treatment at purpose of an antibioticotherapia.

Route of administration and doses:

Accept inside after food.
For prevention of a vitamin mineral deficiency – on 1 tablet once a day. At the states which are followed by the increased need for vitamins and minerals – on 1 tablet 2 times a day. Course of treatment 4 weeks. Repeated courses – according to the recommendation of the doctor.

Features of use:

Coloring of urine in brightly yellow color is possible – absolutely harmlessly and is explained by existence in Riboflavinum drug.

It is not recommended to use Komplivit® along with other drugs containing vitamins and minerals.

Sick diabetes mellitus it is necessary to consider that the content of sugar in the drug Komplivit® makes 92,25 mg (in 1 tablet).

Side effects:

Allergic reactions to drug components are possible.

Interaction with other medicines:

• Iron and calcium detains absorption in intestines of antibiotics from group of tetracyclines and derivative ftorkhinolon. At simultaneous use of vitamin C and sulfanamide drugs of short action the risk of development of a crystalluria increases.
• The antiacid drugs containing aluminum, magnesium, calcium and also Colestyraminum reduce iron absorption. Ascorbic acid increases absorption of drugs of group of penicillin, iron.
• At co-administration of diuretics from group of tiazid the probability of a hypercalcemia increases.  
• _{B6 vitamin} reduces activity of a levodopa at patients with parkinsonism.

Contraindications:

• Hypersensitivity to drug components.
• Children's age up to 12 years.

Overdose:

In case of overdose it is necessary to see a doctor.
Treatment: temporary termination of administration of drug, gastric lavage, reception of absorbent carbon inside, symptomatic treatment.

Storage conditions:

In dry protected from light, the place, unavailable to children, at a temperature not higher than 25 ° C. 

Period of validity - 2 years. Not to use after a period of validity.

Issue conditions:

Without recipe

Packaging:

Tablets, film coated.

On 30, 60, 100 or 365 tablets in banks polymeric. Banks cork the cover screwed. Each can fitted by a cap protective thermoshrinkable together with the instruction on a medical use is placed in a pack from a cardboard. Or banks on 365 tablets with the multipage label containing the full text of the instruction on a medical use fitted by a cap protective thermoshrinkable place in a transport container.