Dolgit 800

General characteristics. Structure:

Active agent: 800 mg of an ibuprofen.

Pharmacological properties:

The ibuprofen reversibly inhibits cyclooxygenase, thereby suppresses synthesis of mediators of an inflammation and pain. After oral administration it is quickly soaked up, the maximum concentration in a blood plasma is reached in 1 — 2 hour. It is quickly metabolized and removed by urine (an elimination half-life about 2 hours).

Indications to use:

Inflammatory and degenerative diseases of joints and backbone. Extraarticular rheumatism. Posttraumatic and postoperative pains, headaches, pain after an exodontia. Dysmenorrhea.

Route of administration and doses:

Dolgit's dosage 800, as a rule, on 1 tablet 2 р / days, the maximum dose 3 р / days, bucketed not less than 8 hours. Do not exceed a daily dose of 2 400 mg. Tablets, coated, accept inside entirely, without chewing, washing down with enough liquid.

Features of use:

Dolgit 800 can adversely influence the activity requiring special attention and bystry decision-making (control of vehicles, works at height). During all administration of drug of Dolgit 800 it is necessary to avoid alcohol intake in any form. Throughout longer course of treatment 800 it is necessary to carry out by drug of Dolgit once a month blood test, analyses of urine and a calla owing to the increased risk of development of sudden bleeding.

Side effects:

As a rule, Dolgit 800 is transferred well (emergence of side effects approximately to 3%). Most often disorders of a GIT meet (nausea, vomiting, heartburn, pain in epigastriums, diarrhea, a lock; more seldom — bleeding from a GIT or change of indicators of function of a liver). Dizziness, headaches, decrease in visual acuity, emotional lability are sometimes observed; in isolated cases hypostases, palpitation, skin allergic reaction, hemopoiesis disturbance; extremely seldom — a renal failure.

Interaction with other medicines:

Simultaneous use of drug of Dolgit 800 with other NPVS or glucocorticoids increases risk of bleeding from a GIT. Dolgit 800 strengthens effect of peroral anticoagulants of a coumarinic row, peroral anti-diabetics of derivatives of sulphonylurea. Dolgit800 at joint reception with acetylsalicylic acid reduces aggregation of thrombocytes. Increases toxicity of a methotrexate and Baclofenum, increases the level of lithium, digoxin and Phenytoinum in a blood plasma. Dolgit 800 can cause decrease in effect of diuretic and anti-hypertensive drugs.

Contraindications:

Hypersensitivity to an ibuprofen, acetylsalicylic acid or other NPVS. Round ulcer of a stomach and duodenum, disturbance of a blood coagulation and hemopoiesis. Children up to 18 years owing to the high content of active ingredient. Only in inevitable cases it is possible to appoint Dolgit to 800 patients with heart failure, arterial hypertension, a heavy abnormal liver function or kidneys, bronchial asthma, nasal polyps, during pregnancy and feeding by a breast.

Overdose:

There are no data on overdose.

Storage conditions:

To store in the place, unavailable to children, in original packaging at a temperature not above 25 °C.

Issue conditions:

According to the recipe

Packaging:

20 tablets, coated, on 800 mg.