Vinpotsetin-LH таб. 0.005 No. 30
Producer: CJSC Lekhim-Kharkiv Ukraine
Code of automatic telephone exchange: N06B X18
Release form: Firm dosage forms. Tablets.
General characteristics. Structure:
International name: Vinpocetine; main physical and chemical properties: tablets of white color; structure: 1 tablet contains a Vinpocetine 0,005 g; excipients: talc, potato starch, lactoses monohydrate, magnesium stearate.
Pharmacological properties:
Pharmacodynamics. Drug strengthens a brain blood stream and improves metabolic processes in a brain. Expands vessels of a brain and strengthens its oxygenation, promotes glucose utilization. Reduces aggregation of thrombocytes. Inhibits phosphodiesterase, increasing the level of cyclic adenosinemonophosphate in fabrics, influencing metabolism of noradrenaline and serotonin.
Pharmacokinetics. After administration of drug inside the Vinpocetine is well and quickly adsorbed from digestive tract. bioavailability of drug makes 70%. The maximum concentration in a blood plasma is noted in 1 hour after reception. Value of therapeutic concentration of a Vinpocetine in plasma is made by from 10 to 20 ng/ml. The elimination half-life makes 4,8 hours.
Indications to use:
Effects of frustration of cerebral circulation (after the had stroke of an atherosclerotic and posttraumatic origin), memory disturbances, dizziness, aphasia. Obstruction of arteries of a retina, secondary glaucomas, vascular reduction of hearing, dizziness of a vestibular origin, vazovegetativny manifestations of a climacteric.
Route of administration and doses:
accept inside 1–2 tablets 3 times a day after food. Improvement comes usually in 1–2 weeks. Duration of a course of treatment makes 2 months. Issues of a possibility of use of drug for children are resolved individually by the doctor depending on a clinical case.
Features of use:
with care appoint drug to patients with a renal failure and coronary heart disease, with a labile arterial pressure, against the background of use of anti-hypertensive means. It is not necessary to accept in operating time with vehicles and mechanisms.
Side effects:
Lowering of arterial pressure, tachycardia, premature ventricular contraction, face reddening, dryness in a mouth, nausea, burning, dizziness, a headache, sleeplessness, drowsiness, weakness, perspiration, allergic reactions.
Interaction with other medicines:
Strengthens action of anti-hypertensive means. At simultaneous use of a Vinpocetine and heparin the risk of development of bleedings increases.
Contraindications:
severe forms of coronary heart disease, cardiac arrhythmias, pregnancy and the period of feeding by a breast, the increased intracranial pressure, the acute period of a hemorrhagic stroke.
Overdose:
So far about cases of overdose of the drug Vinpotsetin-LH it was not reported.
Storage conditions:
In the dry, protected from light place at a temperature from 15 °C to 25 °C. To store in the place, unavailable to children.
Period of validity – 5 years.
Issue conditions:
According to the recipe
Packaging:
on 10 tablets at контурній чарунковій упаковц і, on 3 Abo 5 planimetric charunkovy packagings in пачці картонній.