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Гельминтокс

Препарат Гельминтокс. Innothera Chouzy (Иннотера Шузи) Франция


Producer: Innothera Chouzy (Innoter Shuzi) France

Code of automatic telephone exchange: P02CC01

Release form: Liquid dosage forms. Suspension.

Indications to use: Ankilostomidoz. Enterobiosis. Ascaridosis.


General characteristics. Structure:

Active ingredient: Pyrantelum эмбонат - 14,42 g (in terms of Pyrantelum - 5,0 g);
Excipients:
sorbitol crystallized - 72,10 g
 глицерол - 6,07 g
 polysorbate of 80 - 0,100 g
 lecithin soy - 0,250 g
 povidone - 0,060 g
 citric acid - 0,030 g
 Natrium benzoicum - 0,236 g
 silicone emulsion - 0,050 g
 fragrance blackcurrant – caramel - 0,600 g
 magnesium aluminosilicate - 0,330 g
 the water purified - to 100 ml

Description. Homogeneous suspension of light yellow color with a characteristic smell.
Loss of a deposit can be observed. At agitation of a particle easily again pass into suspension.




Pharmacological properties:

Pharmacodynamics. Protivogelmintny drug causes nervnomyshechny blockade of helminths, sensitive to it, and provides their exile without excitement and stimulation of migration of the struck worms. In a gleam of intestines it is effective against mature and unripe sensitive helminths of both sexes.
It is highly effective against the invasions caused by pinworms (Enterobius vermicularis), ascarids (Ascaris lumbricoides), ankylostomas (Ankylostoma duodenale and Necator americanus).

Pharmacokinetics. Practically it is not absorbed from digestive tract. After reception of a single dose of 12,5 mg/kg concentration in plasma of 0,05-0,13 mkg/ml during 1-3 h. It is metabolized partially in a liver to N-methyl-1,3-propanediamina. Removal through intestines – about 93% in an invariable look, 7% - kidneys in not changed look or in the form of a metabolite.


Indications to use:

 Ascaridosis, enterobiosis (infection with pinworms), анкилостомидоз.


Route of administration and doses:

For intake.
Suspension is intended for children weighing more than 12 kg.
To shake up suspension before the use.
1 ml of suspension contains 50 mg of Pyrantelum,
1 measured spoon – 2,5 ml contains 125 mg of Pyrantelum.
гельминтокс it is possible to accept at any time, without preliminary reception of laxatives, not necessarily on an empty stomach.

Pinworms and ascarids:
At treatment of an enterobiosis and an ascaridosis drug is appointed once in the recommended dose.
Usual dosage – 12,5 mg/kg of weight once, that is:
- to children 6 years are younger: 1 measured spoon of suspension on 10 kg of weight once;
- to children 6 years are more senior: 1 measured spoon of suspension on 10 kg of weight once;
- with an adult weight less than 75 kg: 6 measured spoons once;
- with an adult weight more than 75 kg: 8 measured spoons of suspension once.
For prevention of repeated infection it is recommended to repeat administration of drug in 3 weeks.

Ankylostomas:
In endemia zones, in case of infection of Necator americanus or in case of heavy infection of Ankylostoma duodenale, the dosage makes 25 mg/kg / in day (for one or two receptions) within two-three days, that is:
- to children: 250 mg on 10 kg of weight daily
- with an adult weight less than 75 kg: 1.5 in day
- with an adult weight more than 75 kg: 2 g a day.
In case of Ankylostoma duodenale infection out of endemia zones (proceeds more easily) appoint in a dose in 12,5 mg/kg at one time.


Features of use:

Special preparation and diet at Gelmintoks's appointment is not required.
In case of the available diseases of a liver it is necessary to warn the doctor.
It is necessary to remember that before Gelmintoks's appointment, as well as any other protivogelmintny drug, it is necessary to clean thoroughly the room, to wash up children's toys, before going to bed and after a dream to take a shower and to replace underwear. Bed linen is reasonable in days of treatment and several days after administration of drug to iron the hot iron.
In order to avoid repeated infection it is necessary to follow rules of hygiene strictly: to wash hands, to cut and clean nails, not to allow combing of area of a crotch, to change daily bed and underwear. Treatment of all family members is at the same time recommended. Infection can often not be shown by any symptoms.
After completion of treatment it is necessary to conduct a control research a calla on existence of eggs of helminths.

Influence on ability to manage vehicles
 There are no data on negative influence of drug on ability to manage vehicles and other mechanisms.


Side effects:

From digestive tract: nausea, vomiting, abdominal pains, diarrhea and loss of appetite are seldom noted (most often these symptoms are explained by death of helminths);
Allergic reactions - an itch, urticaria, a dieback;
Slight short-term increase of activity of "hepatic" transaminases;
Headache, dizziness, feeling of fatigue, drowsiness or sleeplessness, hearing disorder, hallucinations, confusion of consciousness, paresthesia, hyperthermia.
If any of the side effects specified in the instruction are aggravated, or you noticed any other side effects which are not specified in the instruction, report about it to the doctor.


Interaction with other medicines:

Simultaneous use of levamisole, piperazin is not recommended. Increases concentration of theophylline in plasma.


Contraindications:

Hypersensitivity to Pyrantelum and other components of drug; myasthenia; liver failure; breastfeeding period.
With care – children's age up to 6 months.

Pregnancy and breastfeeding
 With care appoint drug during pregnancy if the estimated advantage for mother exceeds potential risk for a fruit. There are no data on penetration of drug into breast milk therefore in need of purpose of drug in the period of a lactation it is necessary to stop breastfeeding.


Overdose:

Even the expressed overdose does not cause symptoms of serious intoxication. There is no specific antidote. It is recommended to wash out a stomach and to see a doctor.


Storage conditions:

To store in the dry place protected from light, at a temperature not above 25 °C. To store in the place, unavailable to children. Period of validity 3 years. Not to use drug after a period of validity.


Issue conditions:

According to the recipe


Packaging:

Suspension for intake. On 15 ml in the bottle of brown glass closed by an aluminum cap with screw cutting. 1 bottle with the application instruction and a measured spoon with a capacity of 2,5 ml in a cardboard pack.



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