Rheumatic arthritis

Description:

Rheumatic arthritises are inflammations of joints, the caused immunity disturbances; they can arise at any age.

Symptoms of Rheumatic arthritis:

Against the background of rheumatism or since its beginning at the expressed intoxication, high temperature of a body there is an acute or subacute inflammation of joints. Joints are deformed owing to accumulation in their cavities of inflammatory liquid (synovitis). There is an acute pain. The affected joints acquire the halfbent reflex provision.

Skin temperature over joints is increased, diffuse pain, under skin small knots form. Quite often observe a ring-shaped erythema, a positive symptom of fluctuation, and in a knee joint — balloting of a patella. Srednefalangovy joints porazhutsya very seldom.

After achievement of peak of an acute inflammation deformation of joints disappears, the movements become free, painless, their amplitude is recovered, but at the same time the inflammation of other joints which too completely disappears over time develops. Such volatility of damages of joints is typical for rheumatic polyarthritis or to an oligoarthritis.

There are erased forms poly-or an oligoarthritis. At rheumatic poly-or an oligoarthritis there are never contractures, a hypotrophy of muscles, especially razgibately. Dynamics of changes of a volatility of inflammations in joints accompanies progressing of a rheumatic disease, defeats of visceral bodies and first of all heart. There are a carditis, an endocarditis with clinical manifestations inherent in them.

In blood find a leukocytosis, increase in SOE which expressiveness depends on sharpness of a course of a disease, increase in level of fibrinogen, seromucoid, immunoglobulins. In inflammatory synovial fluid concentration of fibrin, mononuklear considerably increases to 80-95%. Decrease in sharpness of an inflammation of joints with an initiation of treatment salicylates is characteristic of rheumatic arthritis.

Reasons of Rheumatic arthritis:

Development of rheumatic arthritis is connected in autoimmune by reaction of an organism.

Treatment of Rheumatic arthritis:

Radical methods of treatment of rheumatic arthritises do not exist, but the inflammation can be reduced. Medicinal therapy is divided into two big groups: antiinflammatory drugs and antirheumatic drugs.

Antiinflammatory drug are divided into two groups: steroid and nonsteroid drugs. Non-steroidal anti-inflammatory drugs (NPVS) suppress synthesis of mediators of an inflammation. NPVS can be or salicylates like aspirin, or not salicylates as an ibuprofen (BONIFEN, the SNOW-STORM, the NUROFEN).

At rheumatic arthritises as choice drug many doctors apply kishechnorastvorimy forms. However the amount of aspirin necessary for reduction of an inflammation at arthritis creates levels of concentration of drug at which there can be undesirable negative effects. Therapy by high doses of aspirin never has to begin without preliminary survey to define the correct dose and to reach the greatest therapeutic effect at the smallest negative reactions.

Aspirin renders effect at a certain level of concentration in a blood plasma which is various at different people. Therapeutic level of concentration of aspirin lies in the range from 15 to 30 mg on decilitre (10 liters) of blood. To reach this level, it is necessary to take daily from 6 to 15 usual pill (500 mg) of aspirin (from 3 to 7,5 g). If you take aspirin, then it is necessary to trace constantly the level of concentration of aspirin in a blood plasma to prevent intoxication (poisoning). Symptoms of poisoning with aspirin are the sonitus, breath increase (a hyperventilation of lungs), confusion of consciousness, short wind, hypostases of legs and anklebones, the strengthened sweating and thirst. It is necessary to report about these symptoms to the doctor at once.

At constant reception, for example at treatment of rheumatic arthritises, reception of kishechnorastvorimy forms of aspirin is recommended. Researches showed that at reception of kishechnorastvorimy forms of aspirin the necessary level of concentration is reached, but the risk of gastric bleedings in comparison with usual aspirin sharply decreases.

In addition to the efficiency characterizing all protivoartritny drugs of this group, kishechnorastvorimy forms of aspirin are much cheaper than piroxicam. And reception of piroxicam creates the increased risk of development of a peptic ulcer, perforation of intestines and bleedings.

As a rule, all NPVS applied at treatment of rheumatic arthritises are more expensive, than aspirin, big negative effects have and at the same time is not more effective than aspirin. As well as aspirin, other NPVS can cause bleeding in a GIT or a renal failure. If only you had no allergy to aspirin or disturbances of system of digestion at aspirin reception, kishechnorastvorimy forms of aspirin are the best choice at treatment of rheumatic arthritis. However if you have an allergy to aspirin or if you have disturbances of system of digestion at aspirin reception, it is more preferable to use other drug of the NPVS group. Read on the summary to each NPVS of the recommendation about use and information on negative effects. Then choose the drug suitable for you with your doctor.

Other type of antiinflammatory drugs - steroids are very important hormones which perform two functions: regulate an inflammation and control the main vital functions of an organism. As a rule, they are not appointed at the first stage of treatment of rheumatic arthritis. However they can be applied at elderly people who cannot accept NPVS or if they do not render due effect. The intra joint injection is possible if the joint is a source of severe pain. When it is only perhaps recommended to avoid use of steroids as they can cause a large amount of negative effects, including the increased risk of development of the increased fragility of bones, osteoporosis (most possibly at thin women with small bones).

Antirheumatic drugs. In comparison with the above described antiinflammatory drugs, antirheumatic drugs not only remove symptoms, but also can slow down development of the disease. Such antirheumatic drugs as, for example, gold salts, have to be appointed only to patients who suffer from acute forms of rheumatic arthritis and who cannot accept salicylates or other NPVS. The last occurs because more than at 50% of the people accepting antirheumatic drugs it is observed these or those toxic reactions.

Regardless of what drug is chosen for therapy by you and your doctor, it is also necessary to develop the program of physical exercises adequate to your physical state. It will help to strengthen muscles and to keep or improve mobility of joints.

The inflammation can take place and at such rheumatic diseases as an ankylosing spondylarthritis (Bekhterev's disease), a scleroderma, temporary arteritis and a rheumatic polimialgiya. At the same time therapy will be has the same protivovosplitelny focus, as at treatment of rheumatic arthritis.