Strombazhekt Akwa

General characteristics. Structure:

Active ingredient: 50 mg of a stanozolol in 1 ml of suspension.

Excipients: benzyl alcohol, миристил-γ-пиколиния chloride, a macrogoal 400, sodium chloride, water for injections.

Pharmacological properties:

Pharmacodynamics. Stanozolol is steroid anabolic steroid. Getting in a cellular kernel, activates the genetic device of a cell that leads to increase in synthesis of DNA, RNA and structural proteins, activation of enzymes of a chain of tissue respiration and strengthening of tissue respiration, oxidizing phosphorylation, synthesis of ATP and accumulation of makroerg in a cell. Stimulates anabolic and suppresses the catabolic processes caused by glucocorticoids.

Leads to increase in muscle bulk, reduction of adiposities, improves a trophicity of fabrics, promotes adjournment of calcium in bones, detains in an organism nitrogen, phosphorus, sulfur, potassium, sodium and water. Hemopoietic action is connected with increase in synthesis of erythropoetin.

Antiallergic action is caused by increase in concentration of C1 of fraction of a complement. Androgenic activity (low) can promote development of secondary sexual characteristics in men's type.

Indications to use:

Protein synthesis disturbances, cachexia of a different origin; injuries, burns, before - and postoperative the periods, after infectious diseases and radiation; renal and adrenal failure, a toxic craw, muscular dystrophy, osteoporosis, negative nitrogenous balance at corticosteroid therapy, hypo - and aplastic anemia. Supportive application at treatment of tuberculosis, osteomyelitis, bronchial asthma, hepatitis.

Route of administration and doses:

In oil, deeply. The adult an initial dose – 10-20 mg/day. The maintenance dose is equal to 5-10 mg/day.

Treatment is carried out against the background of a protein-rich diet.

Features of use:

At emergence of the first signs of virilescence in women (voice coarsening, a hirsutism, eels, a clitoromegaly), reception should be stopped not to allow irreversibility of changes. To periodically check the level of a lipidemiya and cholesterinemia.

Side effects:

Women have virilescence symptoms, oppression of function of ovaries, frustration of a menstrual cycle, a hypercalcemia.

At men: in the prepubertatny period – virilescence symptoms, an idiopathic hyperpegmentation of skin, delay or the termination of growth (calcification of epiphyseal growth zones of tubular bones); in the post-pubertal period – irritation of a bladder, a gynecomastia, a priapism; at advanced age – a hypertrophy and/or a carcinoma of a prostate.

Men and women have a progressing of atherosclerosis, peripheral hypostases, dispeptic frustration, disturbance of functions of a liver with jaundice, changes in a leukocytic formula, long tubular bone pain, hypocoagulation with bent to bleedings.

Interaction with other medicines:

Glucocorticoids, mineralokortikoida, corticotropin, natriysoderzha-shchy drugs and the food rich with sodium exponentiate a liquid delay in an organism, increase risk of development of hypostases, increase expressiveness of acne rashes.

Strengthens effects of antiagregant, indirect anticoagulants, insulin and peroral antidiabetic means weakens – Somatotropinum and its derivatives.

Contraindications:

Hypersensitivity to drug, a prostate cancer, a breast cancer at men, a carcinoma of a mammary gland at women with a hypercalcemia, an ischemic heart disease, the expressed atherosclerosis, a liver and renal failure, acute and chronic prostatitis, pregnancy, feeding by a breast.

Overdose:

Cases of overdose are not registered.

Storage conditions:

To store at a temperature of 15-25 °C, in dry, protected from light and the place, unavailable to children. Period of validity 3 years. Not to use after the expiry date specified on packaging.

Issue conditions:

According to the recipe

Packaging:

Suspension for injections of 50 mg/ml. On 1 ml and 2 ml in ampoules or on 1 ml, 2 ml and 5 ml in bottles.