medicalmeds.eu Medicines Antiviral means. Гервиракс®, cream of 5%

Гервиракс®, cream of 5%

Препарат Гервиракс®, крем 5%. ОАО "Фармацевтическая фабрика Санкт-Петербурга" Россия

Producer: JSC Pharmaceutical Factory of St. Petersburg Russia

Code of automatic telephone exchange: D06BB03

Release form: Soft dosage forms. Cream.

Indications to use: Herpes infection (Herpes). Genital herpes. (Deprive) the surrounding herpes. Chicken pox (Chicken pox).

General characteristics. Structure:

Active ingredient - an acyclovir of 5 g

Excipients - нипазол, нипагин, A6 cremophore, A25 cremophore, cetyl alcohol, propylene glycol, a liquid paraffin, the water purified.

Description: homogeneous cream of white color.

Pharmacological properties:

Pharmacodynamics. The acyclovir is active concerning Herpes simplex 1 and 2 of types, the Varicella zoster virus, Epstein's virus Barre and cytomegaloviruses. The thymidinekinase of the cells infected with a virus through a number of consecutive reactions actively will transform an acyclovir to mono - di - and acyclovir triphosphate. The last interacts with a virus DNK-polimeraznoy and is built in DNA which is synthesized for new viruses. Thus, "defective" virus DNA forms that leads to suppression of replication of new generations of viruses.

Pharmacokinetics. At local use it is practically not soaked up through the injured skin, does not get to a system blood stream.

Indications to use:

The infections of skin and mucous membranes caused by the Herpes simplex virus of types 1 and 2, genital herpes, shingles, chicken pox.

Route of administration and doses:

Outwardly. Drug is applied by 5 times a day (each 4 hours) with a thin layer on the sites of skin struck and adjoining on them. Cream is applied with either a cotton plug, or clean hands to avoid additional infection of affected areas. Therapy should be continued till that time while on bubbles the crust is not formed or until they completely begin to live. Duration of therapy averages 5 days and should not exceed 10 days.

Features of use:

For achievement of the maximum therapeutic effect it is necessary to begin drug use as soon as possible after the beginning of an infection (at the first symptoms of a disease: burning, itch, pricking, feeling of tension and reddening).

Cream is not recommended to be applied on mucous membranes of an oral cavity and eyes as development of the expressed local inflammation is possible. At treatment of genital herpes it is necessary to avoid sexual contacts or to use condoms as use of an acyclovir does not prevent transfer of a virus to partners.

Side effects:

Hyperemia, dryness, skin peeling; burning, an inflammation at hit on mucous membranes. Development of allergic dermatitis is possible.

Interaction with other medicines:

At external use interaction with other medicines is not revealed.

Contraindications:

Hypersensitivity to an acyclovir and other components of drug.

With care - pregnancy, the lactation period, dehydration, a renal failure.

Storage conditions:

List B. At a temperature from 12 to 15ºC. To store in the place, unavailable to children. A period of validity - 2 years. Not to use after the expiry date specified on packaging.