Hepilor (spray)

General characteristics. Structure:

Active ingredients: Hexetidinum, sincaline salicylate, chlorbutanol гемигидрат;

1 ml of spray contains Hexetidinum in terms of 100% substance of-1 mg, sincaline of salicylate of 80% in terms of 100% substance of-5 mg, chlorbutanol of a gemigidrat in terms of 100% anhydrous substance – 2,5 mg;

excipients: ethanol (96%), sodium saccharin, polysorbate 20, propionic acid, oil lemon, oil anisic, menthol (left menthol), eucalyptole, the water purified.

Pharmacological properties:

Effect of drug is caused by three active ingredients.

Antibacterial and antifungal activity.

Hexetidinum has antibacterial influence both on gram-positive, and on gram-negative strains of microorganisms, both on aerobes, and on anaerobe bacterias.

It should be noted that on aerobic strains it has, generally bacteriostatic influence, bactericidal action weak. The mechanism of action consists in competitive action with thiamin: the structure of Hexetidinum is similar to structure of the thiamin necessary for growth of microorganisms.

Antiinflammatory activity.

Sincaline salicylate possesses analgesic, febrifugal and antiinflammatory action. For treatment of diseases of an oral cavity.

The anesthetizing activity is provided with chlorbutanol. Apply in otolaryngology (drops in a nose, rinsings) and in dental practice (applications and irrigation) as an antiseptic agent.

Active agents are fixed on a mucous membrane of an oral cavity from where they are gradually released.

Indications to use:

Topical treatment of infectious diseases of an oral cavity and throat: quinsies, acute and adenoid diseases, pharyngitises, laryngitis; ulites, stomatitises, afta.

Care of an oral cavity after dental interventions.

Route of administration and doses:

Apply locally to irrigation of an oral cavity.

To adults and children 15 years are more senior:  1 spraying of 4-6 times a day.

Children are from 6 to 15 years old: 1 spraying 2-3 times a day.

Course of treatment no more than 5 days.

Features of use:

At use drug not to swallow and avoid contact with eyes as drug contains ethanol.

Prolonged use as natural microbic balance of an oral cavity and a throat where there is a risk of bacterial or fungal distribution can change is not recommended.

At emergence of the general clinical signs of a bacterial infection the general antibacterial therapy has to be provided.

If symptoms remain more than 5 days and/or body temperature is increased, then it is necessary to reconsider treatment tactics.

Use during pregnancy or feeding by a breast

During pregnancy or feeding by a breast drug is used only on doctor's orders and only in that case when the advantage of use of drug for mother exceeds risk for a fruit.

Ability to influence speed of response at control of motor transport or work with other mechanisms

It is not known.

Children

It is not necessary to use drug to children under 6 years.

Side effects:

Drug can cause allergic reactions: slight irritation of a mucous membrane of an oral cavity, skin reactions; disturbance of flavoring perceptions and sense of smell is possible. In this case it is necessary to stop treatment.

Risk of a sensitization to one of drug components.

Interaction with other medicines:

Not to apply together with the drugs containing antiseptic agents.

Contraindications:

Children's age up to 6 years. The revealed allergy to drug components. Hypersensitivity to any of drug components.

Overdose:

Messages on overdose of drug were not.

Storage conditions:

Period of validity 2 years. Not to use drug after the termination of the period of validity specified on packaging. To store in the place, unavailable to children, at   a temperature not above 25 °C. Not to freeze.

Issue conditions:

Without recipe

Packaging:

On 20 ml or on 50 ml in a bottle. On 1 bottle in a pack.