Coldrex Hotr lemon

General characteristics. Structure:

Active agents: paracetamol of 750 mg, Phenylephrinum hydrochloride of 10 mg, ascorbic acid of 60 mg.

Excipients: citric acid, saccharin of sodium, sodium citrate, sucrose (3 g), lemon tetrarum of 100%, lemon fragrance, quinolinic yellow.

Pharmacological properties:

Means for elimination of symptoms of ORZ and "cold".

Indications to use:

Elimination of symptoms of "cold" and flu:

• the increased temperature,
• headache,
• fever,
•  joint pain and muscles,
• nose congestions,
• pains in bosoms of a nose and in a throat.

Route of administration and doses:

 To pour out contents of 1 bag in a mug, to pour hot water, to stir before dissolution. If it is necessary, to add cold water and sugar. Adults: one bag each 4–6 hours. Not to accept more than 4 bags within 24 hours. Not to accept drug more often than in 4 hours. Children are more senior than 12 years: one bag each 6 hours. Not to accept more than 3 bags within 24 hours.

Not to give drug to children up to 12 years without doctor's instructions.

It is not recommended to apply more than 5 days without consultation of the doctor. If symptoms remain, see a doctor.

 Do not exceed the specified dose. In case of overdose even at good health urgent medical care since there is a risk of the delayed serious damage of a liver is necessary. A specific antidote at poisoning with paracetamol — Acetylcysteinum.

Features of use:

Before administration of drug consultation of the doctor is necessary in a case: reception of Metoclopramidum, domperidon, holestiramin, anticoagulants (warfarin); need of observance of a hyposodium diet (each bag contains 0,12 g of sodium).

In order to avoid toxic damage of a liver paracetamol should not be combined with reception of alcoholic beverages, and also to accept to the persons who are chronically taking alcohol.

As active components of drug do not render sedation, at reception in the recommended doses of restrictions on driving of the car and work with mechanisms is not present.

Side effects:

Paracetamol seldom causes side effects. Allergic reactions are sometimes possible: skin rash, small tortoiseshell, Quincke's disease. Seldom — thrombocytopenia, a leukopenia, an agranulocytosis. At long exceeding of a dose there can be a hepatotoxic and nephrotoxic action. The risk of a hepatotoxic action increases at a concomitant use of barbiturates, dipheninum, carbamazepine, rifampicin, a zidovudine and other inductors of enzymes of a liver.

Phenylephrinum can make sick, a headache, slight increase of blood pressure and is extremely rare heartbeat which pass at the termination of administration of drug. At emergence of unusual reaction see a doctor.

Interaction with other medicines:

Strengthens effects of MAO inhibitors, sedatives, ethanol. Antidepressants, protivoparkinsonichesky and antipsychotic means and derivatives of a fenotiazin increase risk of an ischuria, dryness in a mouth, a lock. Glucocorticosteroids increase risk of development of glaucoma. Paracetamol reduces efficiency of diuretic drugs. The halothane increases risk of ventricular arrhythmia. Fenilefrin reduces hypotensive effect of a guanetidin. Guanetidin strengthens alpha адреностимулирующий, and tricyclic antidepressants — sympathomimetic effects of Phenylephrinum.

Contraindications:

• Hypersensitivity to any component of drug
• The expressed abnormal liver functions and kidneys
• Hyper thyroidism (thyrotoxicosis)
• Diabetes mellitus and inherited disorders of absorption of sugar (contains sugar)
• Heart diseases (the expressed stenosis of the mouth of an aorta, an acute myocardial infarction, tachyarrhythmias)
• Arterial hypertension
• Reception of tricyclic antidepressants, beta adrenoblockers, MAO inhibitors,  including during the period up to 14 days after cancellation
• Reception of others paracetamol - the containing means and means for relief of symptoms of cold, flu and a congestion of a nose
• Prostate adenoma
• Closed-angle glaucoma
• Age up to 12 years.

To apply with care at genetic absence dehydrogenase glyukozo-6-phosphate, at high-quality hyperbilirubinemias, during pregnancy and feeding by a breast.

Overdose:

Drug should be accepted only in the recommended doses. The overdose is caused, as a rule, by paracetamol. Are possible: pallor of integuments, anorexia, nausea, vomiting, гепатонекроз, increase in activity of "hepatic" transaminases, increase in a prothrombin time. At the phenomena of overdose it is urgent to see a doctor.

Treatment: a gastric lavage with the subsequent purpose of absorbent carbon; symptomatic therapy.

Storage conditions:

In the place, unavailable to children, at a temperature not above 25ºC.Срок the validity - 3 years. Do not use after the period of validity specified on packaging.

Issue conditions:

Without recipe

Packaging:

Powder for preparation of solution for intake lemon. On 5 g in bags from a laminate (BPFP). 5 or 10 bags together with  the application instruction place in a cardboard pack. 50 bags place in a cardboard pack (for issue from drugstores on one bag). The full text of the application instruction approved by MZ Russian Federation is applied on a bag.