Hyoxysonum

General characteristics. Structure:

100 g of ointment contain: Hydrocortisoni acetas – 1 g, hydrochloride Oxytetracyclinum (with activity of 860 PIECES/mg) – 3 g and excipients (нипагин, a liquid paraffin, vaseline medical) – to 100 g.

Pharmacological properties:

The combined drug, oppresses development of inflammatory reactions of skin, especially allergic origin complicated by a bacterial infection as a result of total action of the components which are a part of drug. Oxytetracyclinum - an antibiotic from group of tetracyclines, has bacteriostatic action. It is active concerning gram-positive and gram-negative bacteria, Rickettsia spp., Treponema spp., Chlamydia spp., Mycoplasma spp. The hydrocortisone – a glucocorticosteroid, renders antiinflammatory, antiallergic, anti-exudative and antipruritic effects. Slows down phagocytosis; reduces synthesis of prostaglandins and leukotrienes by oppression of activity of a phospholipase of A2 and reduction of release of arachidonic acid from phospholipids of cellular covers. Release of interleykin, etc. the cytokines causing inflammatory process oppresses; slows down release of a histamine and emergence of local allergic reactions. Reduces protein synthesis and adjournment of collagen in skin, interferes with development of connecting fabric, weakens proliferative processes.

Indications to use:

At adults and children 8 years are more senior: the infected intertrigo, folliculites, a furunculosis, an anthrax, impetigo, an ugly face;

the infected eczemas and wounds, erosion;

small tortoiseshell of the newborn;

simple and allergic dermatitis, seborrhea;

solar erythema;

multiformny exudative erythema;

stings of insects;

allergic and purulent diseases of outside acoustical pass;

varicose ulcers of a shin, burns, freezing injuries.

Route of administration and doses:

Locally, outwardly. Ointment in number of 0,5-1 g is applied a thin layer on affected areas of skin by 1-3 times a day or under a sterile gauze bandage. Duration of treatment is individual.

Features of use:

During treatment it is not necessary to carry out by glucocorticosteroids vaccination against smallpox and to plan other types of immunization during treatment (in connection with immunodepressive effect of glucocorticosteroids). 

In need of use of drug on face skin, treatment has to be short, in connection with the increased absorption and a possibility of emergence of side effect.

Side effects:

Are seldom possible – allergic reactions, irritation of skin, an itch, rash. At prolonged use and/or drawing on big surfaces - system side effects of glucocorticoids. At use on face skin – telangiectasias, an atrophy of hypodermic cellulose in a mouth are possible.

Contraindications:

Hypersensitivity to drug components, a tuberculosis cutis, skin tumors, precancerous states, mycosis, viral diseases of skin (herpes, chicken pox); pregnancy, the lactation period (at use on the extensive centers of defeat).

Storage conditions:

List B. In the dry place, at a temperature from 12 to 15 °C. To store in the place, unavailable to children.

Issue conditions:

According to the recipe

Packaging:

Hyoxysonum ointment on 10 g in tubas.